Книга: Время живых машин. Биологическая революция в технологиях
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1

Обозначение для преподавателей, которые в связи с преклонным возрастом освобождены от исполнения своих ежедневных обязанностей. – Прим. пер.

2

P. Sharp, T. Jacks, and S. Hockfield, “Capitalizing on Convergence for Health Care,” Science 352, no. 6293 (2016): 1522–1523, ; Phillip Sharp and Susan Hockfield, “Convergence: The Future of Health,” Science 355, no. 6325 (2017): 589, .

3

Департамент по экономическим и социальным вопросам ООН, демографический отдел “Перспективы мировой урбанизации, редакция 2018 г.”, 2018, .

4

Chunwu Zhu et al.,“Carbon Dioxide (CO2) Levels This Century Will Alter the Protein, Micronutrients, and Vitamin Content of Rice Grains with Potential Health Consequences for the Poorest Rice-Dependent Countries,” Science Advances 4, no. 5 (2018): 1–8, .

5

John A. Church and Neil J. White, “A 20th Century Acceleration in Global Sea-Level Rise,” Geophysical Research Letters 33, no. 1 (2006): 94–97, ; Benjamin D. Santer et al., “Tropospheric Warming over the Past Two Decades,” Scientific Reports 7, no. 1 (2017): 3–8, .

6

Мальтус Т. Р. Опыт о законе народонаселения. – Петрозаводск: Петроком, 1993.

7

Комплексный проект учета численности народонаселения Великобритании. Последнее изменение – май 29, 2015, .

8

Mark Overton, Agricultural Revolution in England: The Transformation of the Agrarian Economy (Cambridge: Cambridge University Press, 1996); Robert C. Allen, “Tracking the Agricultural Revolution in England,” Economic History Review 52, no. 2 (1999): 209–35, .

9

Susan Hockfield, “The Next Innovation Revolution,” Science 323, no. 5918 (2009): 1147, ; Susan Hockfield, “A New Century’s New Technologies,” Project Syndicate (2015), .

10

Marcella Bombardieri and Jenna Russell, “Female Leadership Signals Shift at MIT,” Boston Globe, August 27, 2004; Arthur Jones, “Susan Hockfield Elected MIT’s 16th President,” TechTalk 49, no. 1 (2004); Katie Zezima, “M.I.T. Makes Yale Provost First Woman to Be Its Chief,” New York Times, August 27, 2004, .

11

Девизом МТИ является латинское выражение “Головой и руками” (лат. Mens et Manus). – Прим. пер.

12

Томас Магнатти в разговоре с автором осенью 2004 г.

13

H. F. Judson, The Eighth Day of Creation: The Makers of the Revolution in Biology (Plainview, NY: CSHL Press, 1996).

14

Rosalind E. Franklin and R. G. Gosling, “Evidence for 2-Chain Helix in Crystalline Structure of Sodium Deoxyribonucleate,” Nature 172, no. 4369 (1953): 156–57; Rosalind E. Franklin and R. G. Gosling, “Molecular Configuration in Sodium Thymonucleate,” Nature 171, no. 4356 (1953): 740–41; J. D. Watson and F. H. Crick, “Molecular Structure of Nucleic Acids: A Structure for Deoxyribose Nucleic Acid,” Nature 171, no. 4356 (1953): 737–38; M. H. F. Wilkins, “Molecular Configuration of Nucleic Acids,” Science 140, no. 3570 (1963):941–50.

15

E. S. Lander et al., “Initial Sequencing and Analysis of the Human Genome,” Nature 409, no. 6822 (2001): 860–921, ; J. C. Venter et al., “The Sequence of the Human Genome,” Science 291, no. 5507 (2001): 1304–51, .

16

Постдипломное обучение – эквивалент аспирантуры в России. По его окончании присуждается степень PhD (лат. Philosophiae Doctor, доктор философии), соответствующая российской степени кандидата наук. – Прим. науч. ред.

17

Cold Spring Harbor Symposia on Quantitative Biology, Molecular Neurobiology, XLVIII, C. S. H. Laboratory, 1983.

18

Процесс реализации генетической информации, которую несет данный ген, – синтез на его основе РНК с возможностью последующего синтеза белка. – Прим. науч. ред.

19

Joseph John Thomson, “XL. Cathode Rays,” The London, Edinburgh, and Dublin Philosophical Magazine and Journal of Science 44, no. 269 (1897): 293–316, .

20

Ernest Rutherford, “LXXIX. The Scattering of α and β Particles by Matter and the Structure of the Atom,” Philosophical Magazine Series 6, 21, no. 125 (1911): 669–88, ; Otto Glasser, “W. C. Roentgen and the Discovery of the Roentgen Rays,” American Journal of Roentgenology 165 (1995): 1033–40; R. F. Mould, “Marie and Pierre Curie and Radium: History, Mystery, and Discovery,” Medical Physics 26, no. 9 (1999): 1766–72, .

21

Национальная академия наук, Кабинет министра внутренних дел, “Биографические воспоминания” – Biographical Memoirs, vol. 61 (Washington, DC: National Academy Press, 1992).

22

Национальная академия наук, Кабинет министра внутренних дел, “Биографические воспоминания” – Biographical Memoirs, vol. 61 (Washington, DC: National Academy Press, 1992).

23

T. A. Saad, “The Story of the M.I.T. Radiation Laboratory,” IEEE Aerospace and Electronic Systems Magazine (October 1990): 46–51.

24

S. James Adelstein, “Robley Evans and What Physics Can Do for Medicine,” Cancer Biotherapy and Radiopharmaceuticals 16, no. 3 (2001): 179–85, .

25

Angela N. H. Creager, “Phosphorus-32 in the Phage Group: Radioisotopes as Historical Tracers of Molecular Biology,” Studies in History and Philosophy of Biological and Biomedical Sciences 40, no. 1 (2009): 29–42, .

26

S. Hertz, A. Roberts, and R. D. Evans, “Radioactive Iodine as an Indicator in the Study of Thyroid Physiology,” Proceedings of the Society for Experimental Bio-logy and Medicine 38 (1938): 510–13; S. Hertz and A. Roberts, “Radioactive Iodine in the Study of Thyroid Physiology: VII. The Use of Radioactive Iodine Thera-py in Hyperthyroidism,” Journal of the American Medical Association 131, no. 2 (1946): 81–86; Derek Bagley, “January 2016: Thyroid Month: The Saga of Radioiodine Therapy,” Endocrine News (January 2016); Frederic H. Fahey, Frederick D. Grant, and James H. Thrall, “Saul Hertz, MD, and the Birth of Radionuclide Therapy,” EJNMMI Physics 4, no. 1 (2017), .

27

Термин означает индивидуальный подход к лечению больных, противоположность лечению усредненного пациента. Методики лечения адаптируются под конкретного пациента, однако создание уникальных для него препаратов или методов не предполагается. – Прим. пер.

28

. MIT Reports to the President 73, no. 1 (1937): 19–113; Karl T. Compton and John W. M. Bunker, “The Genesis of a Curriculum in Biological Engineering,” Scientific Monthly 48, no. 1 (1939): 5–15.

29

. MIT Reports to the President 80, no. 1 (1944): 8.

30

Национальная академия наук, Кабинет министра внутренних дел, “Биографические воспоминания” – Biographical Memoirs, vol. 61 (Washington, DC: National Academy Press, 1992).

31

Управление денежными и сырьевыми ресурсами, товарами и услугами компании электронным способом через интернет. – Прим. пер.

32

Вычислительная сеть физических объектов / “вещей”, оснащенных встроенными технологиями для взаимодействия друг с другом или с внешней цифровой средой. – Прим. пер.

33

Janelle R. Thompson et al., “Genotypic Diversity within a Natural Coastal Bacterioplankton Population,” Science 307, no. 5713 (2005): 1311–13, ; Dikla Man-Aharonovich et al., “Diversity of Active Marine Picoeukaryotes in the Eastern Mediterranean Sea Unveiled Using Photosystem-II psbA Transcripts,” ISME Journal 4, no. 8 (2010):1044–52, .

34

Kristala Jones Prather et al., “Industrial Scale Production of Plasmid DNA for Vaccine and Gene Therapy: Plasmid Design, Production, and Purification,” Enzyme and Microbial Technology 33, no. 7 (2003): 865–83, ; Kristala L. Jones Prather and Collin H. Martin, “De Novo Biosynthetic Pathways: Rational Design of Microbial Chemical Factories,” Current Opinion in Biotechnology 19, no. 5 (2008): 468–74, ; Micah J. Sheppard, Aditya M. Kunjapur, and Kristala L. J. Prather, “Modular and Selective Biosynthesis of Gasoline-Range Alkanes,” Metabolic Engineering 33 (2016): 28–40, .

35

Thomas P. Burg et al., “Weighing of Biomolecules, Single Cells and Single Nanoparticles in Fluid,” Nature 446, no. 7139 (2007): 1066–69, ; Nathan Cermak et al., “High-Throughput Measurement of Single-Cell Growth Rates Using Serial Microfluidic Mass Sensor Arrays,” Nature Biotechnology 34, no. 10 (2016): 1052–59, ; Arif E. Cetin et al., “Determining Therapeutic Susceptibility in Multiple Myeloma by Single-Cell Mass Accumulation,” Nature Communications 8, no. 1 (2017), .

36

Hannah Seligson, “Hatching Ideas, and Companies, by the Dozens at M.I.T.,” New York Times, November 24, 2012, ; Joel Brown, “MIT Scientist Robert Langer Talks about the Future of Research,” Boston Globe, May 8, 2015, .

37

Sandra R. Whaley et al., “Selection of Peptides with Semiconductor Binding Specificity for Directed Nanocrystal Assembly,” Nature 405, no. 6787 (2000): 665–68, .

38

“Innovators Under 35 2002: Angela Belcher,” MIT Technology Review, 2002, .

39

“MacArthur Fellows Program: Angela Belcher,” 2004, .

40

Награда, которая ежегодно предоставляется Фондом Джона и Кэтрин Макартуров гражданам или резидентам США, обычно от 20 до 40 лет, работающим в любой отрасли и “демонстрирующим исключительные достижения и потенциал для долгой и плодотворной творческой работы”. Иногда награду называют “грантом для гениев”. – Прим. пер.

41

J. R. Minkel, “Scientific American 50: Research Leader of the Year,” Scientific American, November 12, 2006, .

42

Галиотисы (лат. Haliotis) также известны как абалоны (англ. Abalone), или морские ушки. – Прим. науч. ред.

43

A. M. Belcher et al., “Control of Crystal Phase Switching and Orientation by Soluble Mollusc-Shell Proteins,” Nature 381, no. 56–58 (May 1996), .

44

Bettye L. Smith et al., “Molecular Mechanistic Origin of the Toughness of Natural Adhesives, Fibers and Composites,” Nature 399, no. 6738 (1999): 761–63, .

45

Stanislas Von Euw et al., “Biological Control of Aragonite Formation in Stony Corals,” Science 356, no. 6341 (2017): 933–38, .

46

F. Berna et al., “Microstratigraphic Evidence of in Situ Fire in the Acheulean Strata of Wonderwerk Cave, Northern Cape Province, South Africa,” Proceedings of the National Academy of Sciences 109, no. 20 (2012): 1215–20, .

47

W. Roebroeks and P. Villa, “On the Earliest Evidence for Habitual Use of Fire in Europe,” Proceedings of the National Academy of Sciences 108, no. 13 (2011): 5209–14, .

48

Peter J. Heyes et al., “Selection and Use of Manganese Dioxide by Neanderthals,” Scientific Reports 6 (2016), .

49

Albert Einstein, “Uber Einen Die Erzeugung Und Verwandlung Des Lichtes Betreffenden Heuristischen Gesichtspunkt,” Annalen der Physik (Leipzig) 1905, ; A. B. Arons and M. B. Peppard, “Einstein’s Proposal of the Photon Concept – A Translation of the Annalen der Physik Paper of 1905,” American Journal of Physics 33, no. 5 (1964): 367–74.

50

Управление по энергетической информации, отдел энергетических рынков и конечных пользователей энергии, “Ежегодный отчет об энергоресурсах, 2006” (Annual Energy Review 2006), 2007, .

51

0,252 ккал. – Прим. пер.

52

Управление по энергетической информации США, “U.S. Energy Facts Explained.” Последнее изменение – май 19, 2017, .

53

J. R. Petit et al., “Climate and Atmospheric History of the Past 420,000 Years from the Vostok Ice Core, Antartica,” Nature 399, no. 6735 (1999): 429–36, ; NASA Global Climate Change: Vital Signs of the Planet, “Graphic: The Relentless Rise of Carbon Dioxide.” Last modified November 15, 2018, .

54

Имеется в виду американский галлон, равный 3,78541 л. Английский (британский) галлон составляет 4,54609 л. – Прим. науч. ред.

55

Jeffrey S. Dukes, “Burning Buried Sunshine: Human Consumption of Ancient Solar Energy,” Climatic Change 61, no. 1–2 (2003): 31–44, .

56

Yuyu Chen et al., “Evidence on the Impact of Sustained Exposure to Air Pollution on Life Expectancy from China’s Huai River Policy,” Proceedings of the National Academy of Sciences 110, no. 32 (2013): 12936–41, .

57

D. Larcher and J. M. Tarascon, “Towards Greener and More Sustainable Batteries for Electrical Energy Storage,” Nature Chemistry 7, no. 1 (2015): 19–29, .

58

Департамент по экономическим и социальным вопросам ООН, демографический отдел “Перспективы мировой урбанизации, редакция 2018 г.”, 2018, .

59

Группа Всемирного банка “Потребление электроэнергии (киловатт-час на душу населения)”. Последнее изменение – 2014, .

60

Группа Всемирного банка “Потребление электроэнергии (киловатт-час на душу населения)”. Последнее изменение – 2014, .

61

P. A. Abetti, “The Letters of Alessandro Volta,” Electrical Engineering 71, no. 9 (1952): 773–76, .

62

Электролит – вещество, раствор которого проводит электрический ток. – Прим. науч. ред.

63

P. Kurzweil, “Gaston Plante and His Invention of the Lead-Acid Battery – The Genesis of the First Practical Rechargeable Battery,” Journal of Power Sources 195, no. 14 (2010): 4424–34, .

64

Bruno Scrosati and Jurgen Garche, “Lithium Batteries: Status, Prospects and Future,” Journal of Power Sources 195, no. 9 (2010): 2419–30, ; Akira Yoshino, “The Birth of the Lithium-Ion Battery,” Angewandte Chemie – International Edition 51, no. 24 (2012): 5798–5800, .

65

Antti Vayrynen and Justin Salminen, “Lithium-Ion Battery Production,” Journal of Chemical Thermodynamics 46 (2012): 80–85, .

66

Mia Romare and Lisbeth Dahllof, “The Life Cycle Energy Consumption and Greenhouse Gas Emissions from Lithium-Ion Batteries and Batteries for Light-Duty Vehicles,” IVL Swedish Environmental Research Institute Report C 243, 2017.

67

Управление по охране окружающей среды США, “Калькулятор равноценности парниковых газов”. Последнее изменение – сентябрь 2017, .

68

Tesla, “Модель S – лучший автомобиль”. Последнее изменение – 2018, .

69

Sung Yoon Chung, Jason T. Bloking, and Yet Ming Chiang, “Electronically Conductive Phospho-Olivines as Lithium Storage Electrodes,” Nature Materials 1, no. 2 (2002): 123–28, ; Won Hee Ryu et al., “Heme Biomolecule as Redox Mediator and Oxygen Shuttle for Efficient Charging of Lithium-Oxygen Batteries,” Nature Communications 7 (2016), .

70

Nian Liu et al., “A Pomegranate-Inspired Nanoscale Design for Large-Volume-Change Lithium Battery Anodes,” Nature Nanotechnology 9, no. 3 (2014): 187–92, ; Haotian Wang et al., “Direct and Continuous Strain Control of Catalysts with Tunable Battery Electrode Materials,” Science 354, no. 6315 (2016): 1031–36.

71

Dongliang Chao et al., “Array of Nanosheets Render Ultrafast and High-Capacity Na-Ion Storage by Tunable Pseudocapacitance,” Nature Communications 7 (2016): 1–8, .

72

Nancy Trun and Janine Trempy, “Chapter 7: Bacteriophage,” in Fundamental Bacterial Genetics (Hoboken, NJ: Wiley- Blackwell, 2003), 105–25, .

73

Julien Theze et al., “Paleozoic Origin of Insect Large dsDNA Viruses,” Proceedings of the National Academy of Sciences 108, no. 38 (2011): 15931–35, .

74

Живые организмы используют молекулы ДНК для хранения генетической информации, в то время как вирусы используют для этих целей как ДНК, так и РНК. – Прим. науч. ред.

75

J. D. Watson and F. H. Crick “Molecular Structure of Nucleic Acids: A Structure for Deoxyribose Nucleic Acid,” Nature 171, no. 4356 (1953): 737–38; H. F. Judson, The Eighth Day of Creation: The Makers of the Revolution in Biology (Plainview, NY: CSHL Press, 1996).

76

A. D. Hershey and Martha Chase, “Independent Functions of Viral Protein and Nucleic Acid in Growth of Bacteriophage,” Journal of General Physiology 36 (1952): 39–56; Angela N. H. Creager, “Phosphorus-32 in the Phage Group: Radioisotopes as Historical Tracers of Molecular Biology,” Studies in History and Philosophy of Biological and Biomedical Sciences 40, no. 1 (2009): 29–42, .

77

Один нанометр – одна миллионная часть миллиметра, или одна миллиардная часть метра, 10–9 м. – Прим. науч. ред.

78

Метод, позволяющий “проецировать” исследуемый белок на оболочку вируса для его дальнейшего изучения. В 2018 г. за использование фагового дисплея для направленной эволюции антител была присуждена Нобелевская премия по химии. – Прим. науч. ред.

79

К счастью, ученым не пришлось изменять каждую из 2700 копий по отдельности – достаточно было изменить кодирующую ее последовательность в геноме вируса. – Прим. науч. ред.

80

Кисточки на другом конце центральной трубки М13 составляют два других белка – p7 и p9. – Прим. науч. ред.

81

Ki Tae Nam et al., “Genetically Driven Assembly of Nanorings Based on the M13 Virus,” Nano Letters 4, no. 1 (2004): 23–27; Yu Huang et al., “Programmable Assembly of Nanoarchitectures Using Genetically Engineered Viruses,” Nano Letters 5, no. 7 (2005): 1429–34, ; K. T. Nam et al., “Stamped Microbattery Electrodes Based on Self-Assembled M13 Viruses,” Proceedings of the National Academy of Sciences 105, no. 45 (2008): 17227–31, ; Dahyun Oh et al., “M13 Virus-Directed Synthesis of Nanostructured Metal Oxides for Lithium-Oxygen Batteries,” Nano Letters 14, no. 8 (2014): 4837–45, ; Maryam Moradi et al., “Improving the Capacity of Sodium-Ion Battery Using a Virus-Templated Nanostructured Composite Cathode,” Nano Letters 15, no. 5 (2015): 2917–21, .

82

Научный сотрудник, находящийся на временной (1–2 года) ставке после получения степени PhD. – Прим. пер.

83

Изолятор механически разделяет катод и анод, предотвращая короткое замыкание и переход электролита от одного электрода к другому. – Прим. науч. ред.

84

Ki Tae Nam et al., “Virus-Enabled Synthesis and Assembly of Nanowires for Lithium-Ion Battery Electrodes,” Science 312, no. 5775 (2006): 885–88, ; Yun Jung Lee et al., “Biologically Activated Noble Metal Alloys at the Nanoscale: For Lithium Ion Battery Anodes,” Nano Letters 10, no. 7 (2010): 2433–40, .

85

Yun Jung Lee et al., “Fabricating Genetically Engineered High-Power Lithium-Ion Batteries Using Multiple Virus Genes,” Science 324, no. 5930 (2009): 1051–55, ; Dahyun Oh et al., “Biologically Enhanced Cathode Design for Improved Capacity and Cycle Life for Lithium-Oxygen Batteries,” Nature Communications 4 (May 2013): 1–8, .

86

David Chandler and Greg Frost, “Hockfield, Obama Urge Major Push in Clean Ener-gy Research Funding,” MIT Tech Talk 53, no. 20 (2009): 1–8.

87

J. B. Dunn et al., “Material and Energy Flows in the Materials Production, Assembly, and End-of-Life Stages of the Automotive Lithium-Ion Battery Life Cycle,” Argonne National Laboratory Energy Systems Division (2012), .

88

Mia Romare and Lisbeth Dahllof, “The Life Cycle Energy Consumption and Greenhouse Gas Emissions from Lithium-Ion Batteries and Batteries for Light-Duty Vehicles,” IVL Swedish Environmental Research Institute Report C 243, 2017.

89

Управление по энергетической информации, отдел энергетических рынков и конечных пользователей энергии, “Ежегодный отчет об энергоресурсах, 2006” (Annual Energy Review 2006), 2007, .

90

Peter Agre, “The Aquaporin Water Channels,” Proceedings of the American Thoracic Society 3 (2006): 5–13, .

91

P. Agre and J. P. Cartron, “Molecular Biology of the Rh Antigens,” Blood 78, no. 3 (1991): 551–63; Neil D. Avent and Marion E. Reid, “The Rh Blood Group System: A Review,” Blood 95, no. 2 (2000): 375–87.

92

Peter Agre et al., “Purification and Partial Characterization of the Mr 30,000 Integral Membrane Protein Associated with the Erythrocyte Rh (D) Antigen,” Journal of Biological Chemistry 262, no. 36 (1987): 17497–503; A. M. Saboori, B. L. Smith, and P. Agre, “Polymorphism in the Mr 32,000 Rh Protein Purified from Rh (D) – Positive and- Negative Erythrocytes,” Proceedings of the National Academy of Sciences of the United States of America 85, no. 11 (1988): 4042–45, .

93

Peter Agre, “Aquaporin Water Channels: Nobel Lecture,” 2003.

94

H. H. Mitchell et al., “The Chemical Composition of the Adult Human Body and Its Bearing on the Biochemistry of Growth,” Journal of Biological Chemistry 158 (1945): 625–37; ZiMian Wang et al., “Hydration of Fat-Free Body Mass: Review and Critique of a Classic Body-Composition Constant,” American Journal of Clinical Nutrition 69 (1999): 833–841.

95

Институт науки о воде Геологической службы США, “Мировые запасы воды”. Последнее изменение – 2 декабря 2016. .

96

Программа оценки водных ресурсов мира ООН, “Ежегодный отчет о развитии мировых водных ресурсов ООН 2015: вода для экологически ответственного мира” (Париж, UNESCO, 2015).

97

Quirin Schiermeier, “Water: Purification with a Pinch of Salt,” Nature 452, no. 7185 (2008): 260–61, ; Peter Gleick, “Why Don’t We Get Our Drinking Water from the Ocean by Taking the Salt out of Seawater?” Scientific American Special Report: Confronting a World Freshwater Crisis (July 23, 2008); Ben Corry, “Designing Carbon Nanotube Membranes for Efficient Water Desalination,” Journal of Physical Chemistry B 112, no. 5 (2008): 1427–34, .

98

George E. Symons, “Water Treatment through the Ages,” American Water Works Association 98, no. 3 (2006): 87–97; Manish Kumar, Tyler Culp, and Yuexiao Shen, “Water Desalination: History, Advances, and Challenges,” The Bridge: Linking Engineering and Society 46, no. 4 (2016): 21–29, .

99

Аристотель. Сочинения. В 4 т. (Серия “Философское наследие”). – М.: Мысль, 1975–1983. (Т. 3. Метеорологика).

100

James E. Miller, “Review of Water Resources and Desalination Technologies,” SAND Report (2003): 1–54, ; T. M. Mayer, P. V. Brady, and R. T. Cygan, “Nanotechnology Applications to Desalination: A Report for the Joint Water Reuse and Desalination Task Force,” Sandia Report (2011): 1–34; Muhammad Wakil Shahzad et al., “Energy-Water-Environment Nexus Underpinning Future Desalination Sustainability,” Desalination 413 (2017): 52–64, .

101

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102

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103

Peter Agre, “Peter Agre – Biographical,” in Les Prix Nobel, ed. Tore Frangsmyr (Stockholm: Nobel Foundation, 2004), .

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105

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107

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108

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109

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