Ссылки

Книга: Умный ген. Какая еда нужна нашей ДНК

Назад: Список рекомендованной литературы

От автора

1. Данные за 1994 год показывают, что каждый житель США в среднем ежегодно употребляет 25,1 кг растительного масла, что соответствует 618 калориям в день. Данные из таблиц на сайте USDA говорят, что в 2014 году потребление растительного масла выросло на 170 процентов по сравнению с 1995 годом. Если предполагать, что в 1994 и 1995 году масла употребили примерно одинаково, то при подсчете данных за 2014 год мы получаем, что каждый житель США в среднем потребляет 1000 калорий в день из растительных масел. Калорийность рациона каждого отдельного американца, естественно, может быть очень разной, но, по оценкам 2015 года, среднестатистический американец съедает 3600 калорий в день, а худые американцы – от 1700 до 3000 калорий в зависимости от того, насколько они активны. Оценки для потребителей, заботящихся о своем здоровье, основаны на личном опыте: большинство таких потребителей готовят дома, поэтому меньше подвергаются воздействию растительных масел. Источники: данные 1995 года – из таблицы 6 в статье Polyunsaturated fatty acids in the food chain in the United States, Am J Clin Nutr, January, 2000, vol. 71, no. 1, pp. 179S-188. Данные 2014 года – из таблиц по адресу www.ers.usda.gov/data-products/ oil-crops-yearbook.aspx.

2. Protein lipoxidation: detection strategies and challenges, Giancarlo Aldini, Redox Biol, August 5, 2015, pp. 253–266.

3. Oral glycotoxins are a modifiable cause of dementia and the metabolic syndrome in mice and humans, Weijing Cai et al, PNAS, April 1, 2014, vol. Ill, no. 13.

4. Changes in breast cancer incidence and mortality in middle-aged and elderly women in twenty-eight countries with Caucasian majority populations, С. Hery et al, Ann Oncol, 2008, 19 (5), pp. 1009–1018.

5. Источник: программа «Surveillance, epidemiology, and end results (SEER)» (www.seer. cancer.gov), район SEER 9, возраст 0-19, ссылка открыта 2 апреля 2016 года, www.curesearch. org/Incidence-Rates-Over-Time

6. www. cdc. gov/heartdiseas е/facts.htm

7. Согласно статистике на 2015 год от Alzheimers.net от 2 апреля 2014 года, http://www. Alzheimers.net/resources/Alzheimers-statistics/

Глава 1

8. Доктор Майкл Декстер, Wellcome Trust.

9. Transposable elements: targets for early nutritional effects on epigenetic gene regulation, Waterland RA, Molecular and Cellular Biology, August 2003, vol. 23, no. 15, pp. 5293–5300.

10. Nutrition and Physical Degeneration, Price W, Price-Pottenger Foundation, 1945, p. 75.

11. Lifetime risk for diabetes mellitus in the United States, Venkat Narayan KM, JAMA, 2003, 290:1884–1890.

12. Guts and grease: the diet of native americans, Fallon S, Wise Traditions.

13. A mechanistic link between chick diet and December in seabirds? Proceedings of the Royal Society of Biological Sciences, vol. 273, no. 1585, February 22, 2006, pp. 445–550.

14. Maternal vitamin D status during pregnancy and childhood bone mass at age nine years: a longitudinal study, Javaid MK, Obstetrical and Gynecological Survey, 61(5):305–307, May 2006.

15. Epigenetic epidemiology of the developmental origins hypothesis, Waterland RA, Annual Review of Nutrition, vol. 27, August 2007, pp. 363–388.

16. См. главу 11

17. The Paleo Diet: Lose Weight and Get Healthy By Eating the Food You Were Designed to Eat, Loren Cordain, Wiley, 2002, p. 39.

18. In Defense of Food: An Eaters Manifesto, Michael Pollan, Penguin, 2008.

Глава 2

19. У нас в организме 10 – 100 триллионов клеток, в каждой клетке – 2–3 метра ДНК, таким образом, всего у нас может быть от 20 до 300 триллионов метров. До Луны всего 3 844 000 000 метров.

20. Pluripotency of mesenchymal stem cells derived from adult marrow, Jiang Y, Nature, July 2002, 4;418(6893):41-9, epub Jun 20, 2002.

21. Epigenetics, the science of change, Environ Health Perspect, March 2006, 114(3): A160-A167.

22. Environmental Health Perspectives, vol. 114, no. 3, March 2006.

23. Toxic optic neuropathy, Indian J Ophthalmol, Mar-Apr 2011, 59(2): 137–141.

24. Epigenetic differences arise during the lifetime of monozygotic twins, Fraga MF, PNAS, July 26, 2005, vol. 102, no. 30, pp. 10604-9.

25. Epigenetics: a new bridge between nutrition and health, Adv Nutr, November 2010, vol. 1: 8-16, 2010.

26. Osteoporosis: Diagnostic and Therapeutic Principles, Clifford J. Rosen, Humana Press, 1996, p. 51.

27. Genetics of osteoporosis, Peacock M, Endocrine Reviews 23 (3): 303–326.

28. The ghost in your genes, частичная расшифровка доступна онлайн по адресу http:// www.bbc.co.uk/sn/tvradio/programmes/horizon/ghostgenes.shtml

29. Accuracy of DNA methylation pattern preservation by the Dnmtl methyltransferase, Rachna Goyal, Richard Reinhardt and Albert Jeltsch, Nucl Acids Res, 2006, 34 (4): 1182–1188 doi 10.1093/nar/gkl002.

30. Age-associated sperm DNA methylation alterations: possible implications in offspring disease susceptibility, Jenkins TG, Aston KI, Pflueger C, Cairns BR, Carrell DT, 2014, PLoS Genet, 10(7).

31. Effects of an increased paternal age on sperm quality, reproductive outcome and associated epigenetic risk to offspring, Rakesh Sharma et al, Reproductive Biology and Endocrinology, 2015, 13:35.

32. Age-associated sperm DNA methylation alterations: possible implications in offspring disease susceptibility, Jenkins TG, Aston KI, Pflueger C, Cairns BR, Carrell DT, 2014, PLoS Genet, 10(7).

33. Epigenetic programming by maternal nutrition: shaping future generations, Epigenomics, August 2010, 2(4):539-49.

34. Transposable elements: targets for early nutritional effects on epigenetic gene regulation, Waterland RA, Molecular and Cellular Biology, August 2003, pp. 5293–5300, vol. 23, no. 15.

35. Decreased birthweights in infants after maternal in utero exposure to the Dutch famine of 1944–1945, LH Lumey, Paediatr Perinat Ep, 6:240-53, 1992.

36. Pregnant smokers increases grandkids asthma risk, Vince G, служба новостей NewScientist.com, 22:00, 11 апреля 2005.

37. Rethinking the origin of chronic diseases, Mohammadali Shoja et al, BioScience, 62,5 (2012): 470–478.

38. Epigenetics: genome, meet your environment, Pray L, vol. 18, issue 13, 14, July 5, 2004.

39. Статья размещена по адресу www.bioinfo.mbb.yale.edu/mbb452a/projects/Dov-S-Greenbaum.html#_edn42

40. Там же.

41. Influence of S-adenosylmethionine pool size on spontaneous mutation, dam methylation, and cell growth of escherichia coli, Posnick, LM, Journal of Bacteriology, November 1999, pp. 6756–6762, vol. 181, no. 21.

42. A unified genetic theory for sporadic and inherited autism, Proc Natl Acad Sei USA, July 31, 2007, 104(31): 12831-12836.

43. Whole-genome sequencing in autism identifies hot spots for de novo germline mutation, Jacob Michaelson et al, Cell, 151,7 (2012): 1431–1442.

44. Feature co-localization landscape of the human genome, Sei Rep, 2016, 6: 20650.

45. The effects of chromatin organization on variation in mutation rates in the genome, Nat Rev Genet, April 16, 2015, (4): 213–223.

46. Закон Ципфа гласит, что если составить гистограмму, отображающую количество слов в языке и частоту их употребления, то график будет линейным на двойной логарифмической шкале с уклоном – z. Он выполняется для всех естественных языков.

47. Hints of a language in junk DNA, Flam F, Science, 266:1320, 1994.

48. Power spectra of DNA sequences in phage and tumor suppressor genes (TSG), Eisei Takushi, Genome Informatics, 13: 412–413 (2002).

49. Mantegna RN et al, Physics Review Letters 73, 3169 (1994).

50. The relation of maternal vitamin A deficiency to microopthalmia in pigs, Hale F, Texas S J Med 33:228, 1937.

51. The modulation of DNA content: proximate causes and ultimate consequences, Gregory TR, Genome Research, vol. 9, issue 4, pp. 317–324, April 1999.

Глава 3

52. Ancient precision stone cutting, Lee L, Ancient American: Archaeology of the Americas Before Columbus, February 1997.

53. Nutrition and Physical Degeneration, Weston A Price, Price-Pottenger Foundation, 1970, p.

279.

54. Там же, стр. 5.

55. Там же.

56. Там же, стр. 1.

57. Там же, стр. 31.

58. Этот аргумент будет подробнее изложен и подкреплен статистикой в следующей главе.

59. Management of genetic syndromes, Suzanne В. Cassidy, Judith E. Allanson, Wiley, March

22, 2010.

60. Nutrition and Physical Degeneration, Price Pottenger Foundation, 1970, p. 12.

61. Effects of malocclusions and orthodontics on periodontal health: evidence from a systematic review, Journal of Dental Education, August 1, 2008, vol. 72, no. 8912-918.

62. Nutrition and Physical Degeneration, Weston A Price, Price Pottenger Foundation, 1945, p. 275.

63. Там же, стр. 274-78.

64. Там же.

65. Influence of vitamin B6 intake on the content of the vitamin in human milk, West KD, Am J Clin Nutr, September 29, 1976, (9):961-9.

66. Nutrition and Physical Degeneration, Weston A Price, Price Pottenger Foundation, 1945, p. 110.

67. Wise Traditions, vol. 8, no. 4, p. 24.

68. Nutrition and Physical Degeneration, Weston A Price, Price Pottenger Foundation, 1945, p. 402.

69. The Ways of My Grandmothers, Beverly Hungry Wolf, Quill, 1982, p. 186.

70. Nutrition and Physical Degeneration, Weston A Price, Price Pottenger Foundation, 1945, pp. 402-03.

71. Vitamins for fetal development: conception to birth, Masterjohn C, Wise Traditions, vol.8, no. 4, winter 2007.

72. Nutrition and Physical Degeneration, Weston A Price, Price Pottenger Foundation, 1945, p. 401.

73. Там же, стр. 402

74. Hiraoka, M, Nutritional status of vitamin A, E, C, Bl, B2, B6, nicotinic acid, В12, folate, and beta-carotene in young women, / Nutr Sei Vitaminol, February 2001, 47(l):20–27.

75. Serum vitamin A concentrations in asthmatic children in Japan, Mizuno Y, Pediatrics International, vol. 48, issue 3, pp. 261-4.

76. Vitamin D inadequacy has been reported in up to 36 percent of otherwise healthy young adults, and up to 57 percent of general medicine inpatients in the United States, from High prevalence of vitamin D inadequacy and implications for health, Mayo Clin Proc, March 2006, 81(3):297-9.

77. Nutrient intakes of infants and toddlers, Devaney B, Journal of the American Dietetic Association, 104 (1), suppl 1, S14-S21 (2004).

78. Less than adequate vitamin E status observed in a group of preschool boys and girls living in the United States, / Nutr Biochem, February 2006, 17(2): 132-8.

79. Vitamin К status of lactating mothers and their infants, Greer FR, Acta Paediatr Suppl, August 1999, 88(430):95-103.

80. Nutritional status of vitamin A, E, C, Bl, B2, B6, nicotinic acid, В12, folate, and beta-carotene in young women, Hiraoka, M. / Nutr Sei Vitaminol, February 2001, 47(l):20–27.

81. Consumption of calcium among African American adolescent girls, Goolsby SL, Ethn Dis, spring 2006, 16(2):476-82.

Глава 4

82. The body beautiful: the classical ideal in ancient greek art, New York Times Art and Design section, May 17, 2015, Alastair Macaulay.

83. The history of fitness, Lance C. Dalleck and Len Kravitz, www.unm.edu/~lkravitz/ Article%20folder/history

84. The Spirit of Vitalism: Health, Beauty and Strength in Danish Art, 1890–1940, Gertrud Hvidberg-Hansen (editor), Gertrud Oelsner (editor), James Manley (translator), Museum Tusculanum Press, February 28, 2011.

85. National Ambulatory Medical Care Survey: 2012 State and National Summary Tables, table 16, открыто по ссылке 22 марта 2016 года: www.cdc.gov/nchs/data/ahcd/namcs_summary/2012_ namcs_web_tables.pdf

86. Effects of pelvic skeletal asymmetry on trunk movement: three-dimensional analysis in healthy individuals versus patients with mechanical low back pain, Spine, vol. 31(3), February 1, 2006.

87. Smiths recognizable patterns of human malformation, Jones KL, 6th ed, September 2005.

88. Evaluation of the palate dimensions of patients with perennial allergic rhinitis, DePreietas FCN, Int J Pediatric Dent, vol. 11, issue 5, p. 365, September 2001.

89. Dentofacial morphology of mouthbreathing children, Preto R, Braz Cent J, vol. 13, no. 2, 2002.

90. Cephalometric comparisons of craniofacial and upper airway structures in young children with obstructive sleep apnea syndrome, Kawashima S, Ear Nose and Throat Journal, July 2000.

91. Sleep apnea-related cognitive deficits and intelligence: an implication of cognitive reserve theory, Achantis M, / Sleep Res, Mar 2005, 12(l):69–75.

92. Central nervous malformations in presence of clefts reflect developmental interplay, Mueller AA, Int J Oral Maxillofac Surg, April 2007, 36(4):289-95, epub January 2007.

93. Body weight, waist-to-hip ratio, breasts and hips: role in judgments of female attractiveness and desirability for relationships, Singh D, Ethology and Sociobiology, 16, 1995, pp. 483–507.

94. Waist-to-hip ratio and body dissatisfaction among college women and men: the moderating role of depressed symptoms and gender, Joiner T, Int J Eating Disor, 16, 1994, pp. 199–203.

95. Appearance of symmetry, beauty and health in human faces, Zaidel DW, Brain and Cognition, 57, 2005, pp. 261–263.

96. Waist-to-hip ratio and body dissatisfaction among college women and men: the moderating role of depressed symptoms and gender, Joiner T, Int J Eating Disor, 16, 1994, pp. 199–203.

97. Physical attractiveness, dangerousness, and the Canadian criminal code 1, Esses V, Journal of Applied Social Psychology, 18 (12), pp. 1017–1031.

98. Cross-cultural implications of physical attractiveness stereotypes in personnel selection, Shahani-Denning C, Presentation at 27th Annual Conference on Personnel Assessment, www. ipmaac.org/conf/03/shahani-denning.pdf

99. Подробнее о маске можно узнать на сайте доктора Марквардта: www.Beautyanalysis.com

100. В этом четырехсерийном сериале ВВС очень интересно рассматривается научная основа красоты лица, выражений лица и славы. Подробнее по ссылке: www.imdb.com/title/ tt0280262/

101. Zeising, Adolf, 1854, Neue Lehre von den Proportionen des menschlichen Körpers aus einem bisher unerkannt gebliebenen, die ganze Natur und Kunst durchdringenden morphologischen Grundgesetze entwickelt und mit einer vollständigen historischen Uebersicht der bisherigen Systeme begleitet, Leipzig: Weigel.

102. Mathematical lives of plants: why plants grow in geometrically curious patterns, Julie J. Rehmeyer, July 21, 2007, www.mywire.com/pubs/ScienceNews/2007/07/21/4250760

103. Цитата из рецензии Саймона Сингха на книгу Иана Стюарта Natures Numbers в газете Sunday Telegraph за 11 июля 1998 года.

104. Chaotic climate dynamics, Selvan AM, Luniver Press, 2.

105. A superstring theory for fractal spacetime, chaos and quantumlike mechanics in atmospheric flows, AM Selvan and Suvarna Fadnavis, published with modification in Chaos, Solitons, and Fractals, 10(8), pp. 1321–1334, 1999.

106. Language in context: emergent features of word, sentence, and narrative comprehension, Xu J, Neuroimage, Aprl 15, 2005, 25(3):1002-15.

107. The effect of emergent features on judgments of quantity in configural and separable displays., Peebles D, / Exp Psychol Appl, Jun 14, 2008, (2):85-100.

108. Survival of the Prettiest: The Science of Beauty, Nancy Etcoff, Anchor, reprint edition July 11,2000, p. 34.

109. Facial symmetry and judgments of apparent health support for a “good genes” explanation of the attractiveness-symmetry relationship, Jones BC, Evolution and Human Behavior, vol. 22, issue 6, November 2001, pp. 417–429.

110. An objective system for measuring facial attractiveness, Bashour M, Plast. Reconstr. Surg, 118: 757, 2006, Chapter 3, figure 8. «Клетчатые узоры запускают организованные волны ЭЭГ», цитата по: Lack of long-term cortical reorganization after macaque retinal lesions, Nature, vol.

435, May 2005; см. рисунок 2 и текст о реакции коры на бессистемные изображения. Внимательный взгляд позволяет “оптимизировать сенсорную интеграцию в кортикоталамических нервных путях», цитата по: Thalamic bursting in rats during different awake behavioral states, Proc Natl Acad Sei USA, 2001, 98:15330-15335. Наш мозг реагирует на узоры: Spatial frequency modulates visual cortical response to temporal frequency variation of visual stimuli: an fMRI study, Physiol Meas, 28, pp. 547–554. Симметричные объекты вызывают приток крови к центрам удовольствия: Sex, beauty, and the orbitofrontal cortex, International Journal of Psychophysiology, vol. 63, issue 2, February 2007, pp. 181–185. Младенцы предпочитают и выучивают симметричные изображения быстрее, чем несимметричные: The effect of stimulus attractiveness on visual tracking in two- to six-month-old infants, Infant Behavior and Development, vol. 26, no. 2, April 2003, pp. 135–150(16).

111. Информация получена по ссылке www.fitdeskjockey.com/female-body-types

112. Waist and hip circumferences and all-cause mortality: usefulness of the waist-to-hip ratio? Bigaard J, Nature Obesity, vol. 28(6), June 2004, pp. 741–747.

113. Waist circumference and body composition in relation to all-cause mortality in middle-aged men and women, Bigaard J, Int J Obes (London), July 2005, 29(7):778-84.

114. The shape of things to wear: scientists identify how womens figures have changed in fifty years, Helen McCormack, Independent UK, November 21, 2005.

115. Survival of the Prettiest: The Science of Beauty, Nancy Etcoff, Anchor, reprint edition July 2000, p. 12.

116. Anthropometric and biochemical characteristics of polycystic ovarian syndrome in South Indian women using aes-2006 criteria, Sujatha Thathapudi et al, Int J Endocrinol Metab, 5, 12(1), epub January 2014, 5.

117. Abdominal obesity and hip fracture: results from the Nurses’ Health Study and the Health Professionals Follow-up Study, Haakon Meyer et al, Osteoporosis Inti, 27, 6 (2016):2127-36.

118. Comparison of anthropometric measures as predictors of cancer incidence: a pooled collaborative analysis of eleven Australian cohorts, Jessica Harding et al, Int J Cancer, 137, 7(2013), pp. 1699-708.

119. Apolipoprotein epsilon 4 allele modifies waist-to-hip ratio effects on cognition and brain structure, Daid Zade et al, J Stroke, Cerebrovasc Dis. 22, 2 (2013): 119–125.

120. Adiposity assessed by anthropometric measures has a similar or greater predictive ability than dual-energy X-ray absorptiometry measures for abdominal aortic calcification in communitydwelling older adults, Xianwen Shang et al, Int J Cardiovasc Imaging (2016), doi 10.1007/sl0554-016-0920-2.

121. Waist circumference and body composition in relation to all-cause mortality in middle-aged men and women, Bigaard J, Int J Obes (London)., July 2005, 29(7):778-84.

Глава 5

122. The impact of parity on course of labor in a contemporary population, Vahratian A, Hoffman MK, Troendle JF et al, Birth, March 2006, 33(l):12-7.

123. Nutritional supplements in pregnancy: commercial push or evidence based? Glennville M Curr, Opin Obstet Gynecol, December 2006, 18(6):642-7.

124. The Contribution of Nutrition to Human and Animal Health, Widdowson (editor), Cambridge University Press, p. 263.

125. Reduced brain DHA content after a single reproductive cycle in female rats fed a diet deficient in N-3 polyunsaturated fatty acids, Levant B, Biol Psychiatry, November 1, 2006, 60(9):987-90.

126. Maternal parity and diet (n-3) polyunsaturated fatty acid concentration influence accretion of brain phospholipid docosahexaenoic acid in developing rats, Levant B, / Nutr, January 2007, 137(l):125-9.

127. Change in brain size during and after pregnancy: study in healthy women and women with preeclampsia, American Journal of Neuroradiology, vol. 37, issue 3, pp. 19–26.

128. Как мы узнаем в следующих главах, растительные масла и избыток сахара в диете вносят большой вклад в состояние метаболического дисбаланса, называемое окислительным стрессом. Окислительный стресс, в свою очередь, портит сигнальную функцию клеток, нарушая передачу короткоживущих сигнальных молекул вроде оксида азота и лишая клетку антиоксидантов, необходимых для нормального функционирования, а также непосредственно повреждая клетки свободными радикалами.

129. Effects of oxidative stress on embryonic development, Birth Defects, Res C Embryo Today, September 2007, 81(3): 155-62.

130. Diabetes mellitus and birth defects, Correa A, Am J Obstet Gynecol, September 2008, 199(3):237.

131. Epigenetic regulation of metabolism in children born small for gestational age (review), Holness MJ, Curr Opin Clin Nutr Metab Care, July 2006, 9(4):4 82-8

132. Early-life family structure and microbially induced cancer risk, Blaser MJ, PLoS Med,January 2007, 4(l):e7.

133. The effect of birth order and parental age on the risk of type 1 and 2 diabetes among young adults, Lammi N, Diabetologia, December 2007, 50(12):2433-8, epub October 2007.

134. Associations of birth defects with adult intellectual performance, disability and mortality: population-based cohort study, Eide MG, Pediatr Res, June 2006, 59(6):848-53, epub April 2006.

135. Nutritional factors affecting the development of a functional ruminant – a historical perspective, Warner RG, pp. 1-12 in Proc Cornell Nutr Conf Feed Manuf, Syracuse, NY, Cornell University, Ithaca, NY, 1991.

136. The many faces and factors of orofacial clefts, Schutte В, Human Molecular Genetics,1999, vol. 8, no. 10, pp. 1853–1859.

137. The effect of birth spacing on child and maternal health, Beverly Winikoff, Studies in Family Planning, vol 14, no 10, October 1983, pp. 231–245.

138. Does birth spacing affect maternal or child nutritional status? Matern Child Nutr, July 2007, 3(3):151-73, a systematic literature review.

139. Association between birth interval and cardiovascular outcomes at thirty years of age: a prospective cohort study from Brazil, Devakumar D et al, PLoS One, 2016; 11(2).

140. Developmental dysplasia of the hip, Am Fam Physician, October 15, 2006, 74(8): 1310–1316, Stephen K. Storer.

141. A meta-analysis of common risk factors associated with the diagnosis of developmental dysplasia of the hip in newborns, Fur J Radiol, March 2012, 81(3):e344-51.

142. Idiopathic scoliosis: genetic and environmental aspects, Frances V. De George, /. Med Genet, 1967, pp. 4, 251.

143. Risk factors for deformational plagiocephaly at birth and at seven weeks of age: a prospective cohort study, Van Vlimmeren, LA Pediatrics, February 2007, 119(2):e408-18.

144. Asymmetry of the head and face in infants and in children, David Greene, Am J Dis Child, 1931.

145. A common form of facial asymmetry in the newborn infant; its etiology and orthodontic significance, Elena Boder, American Journal of Orthodontics, vol. 39, issue 12, December 1953, pp. 895–910.

146. On the current incidence of deformational plagiocephaly: an estimation based on prospective registration at a single center, Kevin M Kelly, Semin Pediatr Neurol, 11:301–304, 2004, Elsevier.

147. Craniofacial deformity in patients with uncorrected congenital muscular torticollis: an assessment from three-dimensional computed tomography imaging, Yu C–C, Wong F-W, Lo L-J, et al, Plast Reconstr Surg, 2004, 113:24–33.

148. Intrauterine growth retardation (IUGR): epidemiology and etiology, Romo A, Pediatr Endocrinol Rev, February 2009, suppl 3:332-6.

149. Intrauterine growth retardation – small events, big consequences, Taimur Saleem, Ital J Pediatr, 2011, 37: 41.

150. Maternal and fetal indicators of oxidative stress during intrauterine growth retardation (IUGR), Ullas Kamath, Indian J Clin Biochem, March 2006, 21(1): 111–115.

151. Human conditions of insulin-like growth factor-I (IGF-I) deficiency, Juan E Puche, / Transl Med, 2012.

152. Неопубликованная переписка с кандидатом наук из Онкологического центра имени Джонсона в Калифорнийском университете в Лос-Анджелесе, 11 октября 2006.

153. Лиллиан Гелберг, Онкологический центр имени Джонсона в Калифорнийском университете в Лос-Анджелесе, 11 октября 2006.

154. Vitamin A and beta-carotene supply of women with gemini or short birth intervals: a pilot study, Schulz C, Eur J Nutr, November 10, 2006.

155. From Vitamin profile of 563 gravidas during trimesters of pregnancy, Baker H, / Am Coll Nutr, February 2002, 21(l):33-7.

156. High prevalence of vitamin D insufficiency in black and white pregnant women residing in the Northern United States and their neonates, Bodnar LM, /Nutr, February 2007, 137(2):447-52.

157. Maternal supplementation with very-long-chain in 3 fatty acids during pregnancy and lactation augments childrens IQ at four years of age, Heiland IB, Pediatrics, January 2003, lll(l):e39-44.

158. The fetal origins of memory: the role of dietary choline in optimal brain development, Zeises SH, / Pediatr, November 2006, 149(5 suppl):S131-6, review.

159. Choline: are our university students eating enough? Gossell-Williams M, West Indian Med J, June 2006, 55(3): 197-9.

160. Fetal alcohol syndrome: historical perspectives, Neuroscience and Biobehavioral Reviews, vol. 31, issue 2, 2007, pp. 168–171; and Fetal alcohol syndrome: the origins of a moral panic alcohol and alcoholism, vol. 35, issue 3, May 1, 2000.

161. Prevention of neural tube defects: results of the Medical Research Council Vitamin Study, MRC Vitamin Study Research Group, Lancet, July 20, 1991, 338(8760):131-7.

162. Views: ergot and the salem witchcraft affair: an outbreak of a type of food poisoning known as convulsive ergotism may have led to the 1692 accusations of witchcraft, Mary K. Matos-sian, American Scientist, vol. 70, no. 4, July-August 1982, pp. 355–357.

163. Nutritional supplements in pregnancy: commercial push or evidence based? Glenville M, Current Opinion in Obstetrics and Gynecology, 2006, 18:642–647.

164. Beyond deficiency: new views on the function and health effects of vitamins, Annals of the New York Academy of Sciences, vol. 669, 1992, pp. 8-10.

165. Natural Causes: Death, Lies, and Politics in Americas Vitamin and Herbal Supplement Industry, Dan Hurly, Broadway, 2006.

166. Changes in USDA food composition data for forty-three garden crops, 1950 to 1999, Donald R Davis, P. Journal of the American College of Nutrition, vol. 23, no. 6, 2004, pp. 669–682.

167. Сравнение таблиц в McCance and Widdowson, The chemical composition of foods versions from 1940 and 2002, published by His Majesty’s Stationery Office, London.

168. Nutritional supplements in pregnancy: commercial push or evidence based? Glenville M, Current Opinion in Obstetrics and Gynecology, 2006, 18:642–647.

169. Traditional methods of birth control in Zaire, Waife RS, Pathfinder Papers No. 4, Chestnut Hill, MA, 1978.

170. “Le bebe en brousse”: European women, African birth spacing and colonial intervention in the Belgian Congo, Hunt NR, International Journal of African Historical Studies, 21, 3 (1988), pp. 401-32.

171. Intimate colonialism: the imperial production of reproduction in Uganda, 1907–1925, Carol Summers, Signs, vol. 16, no. 4, Women, Family, State, and Economy in Africa, Summer 1991, pp. 787–807.

172. Nutrition and Physical Degeneration, Weston A Price, Price Pottenger Foundation, 1945, p. 398.

173. Махатма Ганди, цитата no Richard Frazer, Live as though you might die tomorrow and farm as though you might live forever, Christian faith and the welfare of the city, Johnston R. McKay (editor), Edinburgh: CTPI, 2008, p. 48.

174. Letter to all state governors on a uniform soil conservation law, February 26, 1937, Franklin D Roosevelt, pp. 1933-945.

175. Nutritional supplements in pregnancy: commercial push or evidence based? Glenville M, Current Opinion in Obstetrics and Gynecology, 2006, 18:642–647.

176. Changes in USDA food composition data for forty-three garden crops, 1950 to 1999, Donald R Davis, P. Journal of the American College of Nutrition, vol. 23, no. 6, 2004, pp. 669–682.

177. Сравнение таблиц в McCance and Widdowson, The chemical composition of foods versions from 1940 and 2002, published by His Majesty’s Stationery Office, London.

178. Nutritional supplements in pregnancy: commercial push or evidence based? Glenville M, Current Opinion in Obstetrics and Gynecology, 2006, 18:642–647.

179. Lifetime risk for diabetes mellitus in the United States, Venkat Narayan, KM, JAMA, 2003, 290:1884–1890.

180. Americas children in brief: key national indicators of well-being, 2008, Federal Interagency Forum on Child and Family Statistics.

181. Dairy products and physical stature: a systematic review and meta-analysis of controlled trials, Hans de Beer, Economics and Human Biology, 10,3 (2012), pp. 229–309.

182. Do variations in normal nutrition play a role in the development of myopia? Marion Edwards et al, Optometry and Vision Science, 73, 10 (1996), pp. 638–643.

183. Их несколько; один из примеров: К Chen et al, Antioxidant vitamin status during pregnancy in relation to cognitive development in the first two years of life, Early Hum Dev, 85,7, 2009, pp. 421-27.

184. Maternal fatty acids in pregnancy, FADS polymorphisms, and child intelligence quotient at eight years of age, Colin Steer et al, Am J Clin Nutr, 98, 6, 2013, pp. 1575-582.

185. Dietary patterns in early childhood and child cognitive and psychomotor development: the Rhea mother-child cohort study in Crete, Vasiliki Levantakou et al, British Journal of Nutrition, 1, 8, 2016, pp. 1–7.

186. Recognition of a sequence: more growth before birth, longer telomeres at birth, more lean mass after birth, F de Zegher et al, Pediatric Obesity, doi 10.1111/ijpo. 12137.

187. Muscularity and fatness of infants and young children born small- or large-for-gestational-age, Mary Hediger et al, Pediatrics, 102,5, 1998, E60.

188. The Potential Impact of Nutritional Factors on Immunological Responsiveness, in Nutrition and Immunity, M Eric Gershwin.

189. Early development of the gut microbiota and immune health, M. Pilar Franciino, Pathogens, 3,3, 2014, pp. 769-90.

190. Is dirt good for kids? Are parents keeping things too clean for their kids’ good? Zamosky, Lisa, Medscape, www.webmd.com/parenting/d2n-stopping-germs-12/kids-and-dirt-germs

191. Early puberty: causes and effects, Maron, Dina Fine, Scientific American, Health, May 2, 2015, http://www.scientfficamerican.com/article/early-puberty-causes-and-effects/

192. The regulation of reproductive neuroendocrine function by insulin and insulin-like growth factor-1 (IGF-1), Andrew Wolfe et al, Front Neuroendocrinol, 35,4(2014), pp. 558-72.

193. Anna Stainer-Knittel: portrait of a femme vitale, Kain E, Womens Art Journal, vol. 20, no. 2, pp. 13–71.

194. Mirror, Mirror. . The Importance of Looks in Everyday Life, Hatfield E, SUNY Press, 1986.

195. Stature of early Europeans, Hormones, Hermanussen M, Athens, July-September 2003, 2(3): 175-8.

196. New light on the “dark ages”: the remarkably tall stature of Northern European men during the Medieval era, Steckel RH, Social Science History, 2004, 28(2), pp. 211–229.

197. The Cambridge World History of Food, Cambridge University Press, 2000.

198. Fighting the Food Giants, Paul A Stitt, Natural Press, 1981, pp. 61–66.

Глава 6

199. Ссылка открыта 27 июля 2008 года; www.lostgirlsworld.blogspot.com/2006/12/becom-ing-maasai.html

200. Ссылка открыта 4 сентября 2008 года; www.bluegecko.org/kenya/tribes/maasai/beliefs.

htm

201. The emergence of Orwellian newspeak and the death of free speech, John W Whitehead, Commentary from the Rutherford Institute, June 29, 2015, accessed online on April 1, 2016, at www.rutherford.org/publications_resources/john_whiteheads_commentary/the_emergence_of_or-wellian_newspeak_and_the_death_of_free_speech

202. Nutrition and Physical Degeneration, Weston A Price, Price WA, Price-Pottenger Foundation, 1945, p. 226.

203. Там же, p. 10.

204. Там же, p. 228.

205. Там же, р. 248.

206. Archaeological Amerindian and Eskimo cranioskeletal size variation along coastal Western North America: relation to climate, the reconstructed diet high in marine animal foods, and demographic stress, Ivanhoe F, International Journal of Osteoarchaeology, vol. 8, issue 3, pp. 135–179.

207. Craniofacial variation and population continuity during the South African Holocene, Stynder DD, American Journal of Physical Anthropology, опубликовано в сети.

208. Craniofacial morphology in the Argentine center-West: consequences of the transition to food production, Marina L Sardi, American Journal of Physical Anthropology, vol. 130, issue 3, pp. 333–343.

209. The Cambridge World History of Food, Cambridge University Press, 2000, p. 1704.

210. Stone age economics, Sahlins M Aldine, Transaction, 1972, pp. 1-40.

211. Там же.

212. The question of robusticity and the relationship between cranial size and shape in Homo sapiens, Lahr MM, Journal of Human Evolution, 1996, 31, pp. 157–191.

213. Dental caries in prehistoric South Africans, Dryer TF, Nature, 136:302, 1935, «Показания в этой области… подтверждают опытные данные европейских антропологов: кариес – это сравнительно современная болезнь, и ни один череп со следами этой болезни нельзя считать древним».

214. Dental anthropology, Scott GR, Annual Review of Anthropology, vol. 17:99-126, October 1988, «Ярко выраженные формы малокклюзии появились сравнительно недавно».

215. Bioarchaeology of Southeast Asia, Oxenham M, Cambridge University Press, 2006. «У охотников-собирателей обычно редко встречается кариес, зубной камень, малокклюзия и альвеолярная ресорбция, зато часто наблюдается износ зубов и большой размер челюсти. У земледельцев обычно наблюдается противоположное явление: зубы редко стираются (если еда не содержит абразивных материалов), зато часто наблюдается кариес, зубной камень, ресорбция, кривые зубы и малокклюзия».

216. Fannie Farmer 1896 Boston Cookbook, Fannie Merritt Farmer, Boston Cooking School, Ottenheimer, commemorative edition, 1996, pp. 1–2.

217. Nutrition and Physical Degeneration, Price WA, Price-Pottenger Foundation, 1945, p. 279.

218. Там же.

219. January 20, 2001, inaugural luncheon menu served at the U.S. State Capitol, ссылка открыта 31 октября 2007 года; www.gwu.edu/percent7Eaction/inaulu.html

220. The content of bioactive compounds in rat experimental diets based on organic, low-input, and conventional plant materials, Leifert C, 3rd QLIF Congress, Honeheim, Germany, March 20–23, 2007, доступно по ссылке: www.orgprints.org/view/projects/int_conf_qlif2007.html

221. Nutritional comparison of fresh, frozen, and canned fruits and vegetables, vitamin A and carotenoids, vitamin E, minerals and fiber, Joy C Rickman, / Sei Food Agric.

222. The vitamin A, B, and C content of artificially versus naturally ripened tomatoes, House MC, Journal of Biological Chemistry, vol. LXXXI, no. 3, received for publication December 13, 1928.

223. Там же.

224. Nutritional comparison of fresh, frozen and canned fruits and vegetables, Part 1, Vitamins C and В and phenolic compounds, Joy C Rickman, / Sei Food Agric, 87:930–944 (2007).

Глава 7

225. Types of dietary fat and risk of coronary heart disease: a critical review, HU F, Journal of the American College of Nutrition, vol. 2, 1, 5-19, 2001.

226. In Defense of Food: An Eaters Manifesto, Michael Pollan, Penguin, 2009, p. 43.

227. Eat Fat, Get Thin: Why the Fat We Eat Is the Key to Sustained Weight Loss and Vibrant Health, Mark Hyman, Little, Brown, 2016.

228. The Big Fat Surprise: Why Butter, Meat and Cheese Belong in a Healthy Diet, Nina Teicholz, Simon and Schuster, reprint, 2015.

229. In food choices and coronary heart disease: a population based cohort study of rural Swedish men with twelve years of follow-up, Int J Environ Res Public Health 2009, 6, 2626–2638. Авторы утверждают: «Диетическая гипотеза болезней сердца из 1950-х, согласно которой насыщенные жиры приводят к болезням сердца из-за нарушения функций липидов в крови, сейчас пересматривается». Барри Гровс ссылается более чем на 1000 статей в своей книге Trick and Treat: How Healthy Eating Is Making Us III, Hammersmith, 2008. Столь же хорошо проработана и 640-страничная книга Гэри Тоубса Good Calories, Bad Calories, Knopf 2007.

230. Исследуя медицинскую историю своей семьи, я узнала от мамы, что и ее, и ее брата кормили молочной смесью – так в ту пору было принято среди образованных женщин на Восточном побережье. Я спросила бабушку, почему она решила последовать моде – сама я подозревала, что она так поступила для удобства или, может быть, потому, что думала, что так легче будет сохранить фигуру. К моему удивлению, она пересказала мне историю о встрече с «молочной медсестрой» Nestle после рождения моего дяди. Бабушке сказали, что если она будет кормить грудью, то ей придется принимать разнообразные витаминные добавки, чтобы гарантировать здоровье ребенка. А вот если она будет кормить ребенка смесью, «укрепленной» различными витаминами, то ей не придется давать ребенку ничего дополнительного, потому что смесь «идеальнее грудного молока».

231. Архивная версия программы The Search с Кисом за 1953 год доступна на сайте Университета Миннесоты: www.epi.umn.edu/cvdepi/video/the-search-1953/

232. Health revolutionary: the life and work of Ancel Keys, www.209.85.141.104/ search?q=cache: PVHCLllMKzQJ: www.asph.org/movies/keys.pdf+percent22i’ll+show+those+guysp ercent22+keys&hl=en&ct=clnk&cd= 1 &gl=us&client=firefox-a

233. Hydrogenated fats in the diet and lipids in the serum of man, Anderson JT, / Nutr, 75 (4):338, p. 1961.

234. Там же.

235. Health revolutionary: the life and work of Ancel Keys, www.209.85.141.104/ search?q=cache: PVHCLllMKzQJ: www.asph.org/movies/keys.pdf+percent22i’ll+show+those+guysp ercent22+keys&hl=en&ct=clnk&cd= 1 &gl=us&client=firefox-a

236. Отслеживая ссылки в консенсусных статьях и других исследовательских заявлениях, влияющих на определение политики, мы неизбежно возвращаемся обратно к Кису и его мусорной науке. Вот пример: координационный комитет Национальной холестериновой программы (NCEP) 2004 года издал обновление к консенсусному заявлению третьей Комиссии по лечению взрослых (ATP III).

237. Time magazine, March 26, 1984.

238. Time magazine, Jun 12, 2014.

239. Oxidation of linoleic acid in low-density lipoprotein: an important event in atherogenesis, Spiteller G, Angew Chem Int Ed Engl, February 2000, 39(3):585–589.

240. Know Your Fats: The Complete Primer for Understanding the Nutrition of Fats, Oils, and Cholesterol, Mary G Enig, Bethesda Press, 2000, p. 94.

241. The Cholesterol Myths, Uffe Ravnskov, New Trends Publishing, 2000, p. 30.

242. Myths and truths about beef, Fallon S, Wise Traditions in Food, Farming and the Healing Arts, Spring 2000.

243. Trans fatty acids in the food supply: a comprehensive report covering sixty years of research, second edition, Enig Mary G, Enig Associates, Silver Spring, MD, 1995, pp. 4–8.

244. Heart disease and stroke statistics, 2003 update, American Heart Association.

245. The rise and fall of ischemic heart disease, Stallones RA, Sei Am, Nov 1980, 243(5):53-9.

246. Sex matters: secular and geographical trends in sex differences in coronary heart disease mortality, Lawlor DA, BMJ, September 8, 2001, 323:541–545.

247. The lowdown on oleo, Kapica C, Chicago Wellness Magazine, September-October 2007.

248. См. главу 11

249. The ABCs of vitamin E and ß-carotene absorption, Traber MG, American Journal of Clinical Nutrition, vol. 80, no. 1, July 3–4, 2004.

250. Absorption, metabolism, and transport of carotenoids, Parker RS, FASEB J, April 1996, 10(5):542-51.

251. Human plasma transport of vitamin D after its endogenous synthesis, Haddad JG, Matsuoka LY, Hollis BW, Hu YZ, Wortsman J.

252. Physicochemical and physiological mechanisms for the effects of food on drug absorption: the role of lipids and pH, Journal of Pharmaceutical Sciences, vol. 86, issue 3, pp. 269–282.

253. Plasma lipoproteins as carriers of phylloquinone (vitamin Kl) in humans, Am J Clin Nutr, June 1998, 67(6): 1226-31.

254. Vitamin E: absorption, plasma transport and cell uptake, Hacquebard M, Carpentier YA, Curr Opin Clin Nutr Metab Care, March 2005, 8(2): 133-8.

255. ПНЖК уменьшают выработку постпрандиальных триглицеридов, которые переносят жирорастворимые питательные вещества после вашего последнего приема пищи.

256. «…Сейчас уже появилось понимание, что замена насыщенных жиров растительными маслами, содержащими много полиненасыщенных жирных кислот (ПНЖК), может сделать пациента более восприимчивым к повреждению сердечно-сосудистой системы». In Vivo absorption, metabolism, and urinary excretion of alpha, beta-unsaturated aldehydes in experimental animals: relevance to the development of cardiovascular diseases by the dietary ingestion of thermally stressed polyunsaturate-rich culinary oils, Grootveld MJ, Clin Invest, vol. 101, no. 6, March 1998, pp. 1210-218.

257. Доклад Эниг был опубликован в престижных Food Chemical News и Nutrition Week, а также в других публикациях, которые часто читают члены Конгресса. The oiling of America, posted on January 1, 2000, by Sally Fallon and Mary G. Enig. Подробнее: www.westonaprice.org/ know-your-fats/the-oiling-of-america/#sthash.xgjweoMn.dpuf

258. Dietary oxidized fatty acids: an atherogenic risk? Meera Penumetchaa M, Journal of Lipid Research, vol. 41, 1473–1480, September 2000.

259. Determination of total trans fats and oils by infrared spectroscopy for regulatory compliance, Mossoba M, Anal Bioanal Chem, 2007, 389:87–92.

260. Lipoxygenase-catalyzed oxygenation of storage lipids is implicated in lipid mobilization during germination, Feussner I, Proceedings of the National Academy of Sciences, vol. 92, 11849-11853.

261. Formation of modified fatty acids and oxyphytosterols during refining of low erucic acid rapeseed oil, aka canola oil, Lambelet PJ, Agric Food Chem, July 2003, 16;51(15):4284-90.

262. The effect of short-term canola oil ingestion on oxidative stress in the vasculature of stroke-prone spontaneously hypertensive rats, Lipids Health Dis, October 2011, 17;10:180.

263. Differential effects of dietary canola and soybean oil intake on oxidative stress in stroke-prone spontaneously hypertensive rats, Lipids Health Dis, June 2011, 13;10:98.

264. Formation of modified fatty acids and oxyphytosterols during refining of low erucic acid rapeseed oil, aka canola oil, Lambelet PJ, Agric Food Chem, July 2003, 16;51(15):4284-90.

265. Mastugo et al, Current medicinal chemistry, 1996, vol. 2, no. 4, Bentham Science Publishers, page 764, subheading The chemistry of free radicals and biological substrates, Table 1, Reaction rate constants of hydroxyl radical with organic compounds.

266. Familial hypercholesterolemia: risk stratifications in practice, ReachMD, подкаст Алана Брауна, www.reachmd.com/programs/lipid-luminations/its-relative-screening-and-treating-famil-ial-hypercholesterolemia/6421, комментарии Алана Брауна на 9-й минуте.

267. Testosterone induces erythrocytosis via increased erythropoietin and suppressed hepcidin: evidence for a new erythropoietin/hemoglobin set point, Bachman EJ, Gerontol Biol Sei Med Sei, June 2014, 69(6):725-35, doi 10.1093/gerona/gltl54, epub October 2013.

268. Lipid peroxidation in vivo evaluation and application of methods for measurement by Eva Södergren, comprehensive summaries of Uppsala Dissertations from the Faculty of Medicine, 949.

269. Antioxidant and inhibitory effects of aqueous extracts of Salvia officinalis leaves on pro-oxidant-induced lipid peroxidation in brain and liver in vitro, Oboh G, / Med Food, February 2009, 12(l):77–84.

270. Antioxidant and inhibitory effect of red ginger (Zingiber officinale var. Rubra) and white ginger (Zingiber officinale Roscoe) on Fe(2+) induced lipid peroxidation in rat brain in vitro, Oboh G, Exp Toxicol Pathol, January 2012, 64(l-2):31-6.

271. Autoxidation of human low density lipoprotein: loss of polyunsaturated fatty acids and vitamin E and generation of aldehydes, / Lipid Res, May 1987, 28(5):495–509, www.ncbi.nlm.nih. gov/pubmed/3598395

272. Impaired endothelial function following a meal rich in used cooking fat, Williams M, / Am Coll Cardiol, 1999, 33:1050–1055.

273. Владелец одного местного ресторана рассказал, что одно из самых полезных свойств новых масел для жарки «с меньшим количеством трансжиров» состоит в том, что их срок службы можно продлить с одной недели до двух. К этому времени, по его словам, масло становится уже таким черным и вонючим, что не менять его уже нельзя. Приятного аппетита!

274. Two consecutive high-fat meals affect endothelial-dependent vasodilation, oxidative stress and cellular microparticles in healthy men, Tushuizen ME, / Thromb Haemost, May 2006, 4(5):1003-10.

275. Intake of calories and selected nutrients for the United States population, 1999–2000,опубликовано в Интернете и открыто 4 апреля 2016 года: www.cdc.gov/nchs/data/nhanes/data-briefs/calories.pdf.

276. A new role for apolipoprotein E: modulating transport of polyunsaturated phospholipid molecular species in synaptic plasma membranes, / Neurochem, January 2002, 80(2):255-61.

211. Oxidation of linoleic acid in low-density lipoprotein: an important event in atherogenesis, Angew, Chem Int Ed, 2000, 39, no. 3.

278. / Lipid Res, May 1987, 28(5):495–509, Autoxidation of human low density lipoprotein: loss of polyunsaturated fatty acids and vitamin E and generation of aldehydes, at: www.ncbi.nlm.nih.gov/ pubmed/3598395

279. Oxidation of linoleic acid in low-density lipoprotein: an important event in atherogenesis, Angew, Chem Int Ed, 2000, 39, no. 3.

280. Non enzymatic glycation of apolipoprotein A-I: effects on its self-association and lipid binding properties, Calvo C, Biochem Biophys Res Commun, June 3, 1988, 153(3): 1060-7.

281. Stone NJ, et al, 2013 ACC/AHA blood cholesterol guideline, p. 1, 2013, ACC/AHA guideline on the treatment of blood cholesterol to reduce atherosclerotic cardiovascular risk in adults, a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines.

282. Cholesterol and cancer: answers and new questions, Eric J Jacobs, Cancer Epidemiol Biomarkers Prev, November 2009, 18; 2805.

283. U. Ravnskov, High cholesterol may protect against infections and atherosclerosis, Q / Med, 2003, 96: 927–934.

284. Cholesterol quandaries relationship to depression and the suicidal experience, Randy A Sansone, Psychiatry (Edgmont), March 2008; 5(3): 22–34.

285. Editorial serum cholesterol concentration, depression, and anxiety, Mehmed УиЁсе1 Agl-argufin, A eta Psychiatr Scand, 2002: 105: 81 ±83.

286. Low cholesterol as a risk factor for primary intracerebral hemorrhage: a case-control study, Ashraf V. Valappil, Ann Indian Acad Neurol, January-March 2012; 15(1): 19–22.

287. Chronic kidney disease and its complications, Robert Thomas, Prim Care, Jun 2008, 35(2): 329-vii.

288. High density lipoprotein as a protective factor against coronary heart disease, Tavia Gordon et al, The Framingham Study, American Journal of Medicine, May 1977, vol. 62, pp. 707–714.

289. www.cvriskcalculator.com/

290. Oxidation of linoleic acid in low-density lipoprotein: an important event in atherogenesis, Spiteller D, Spiteller G. Angew, Chem Int Ed Engl, February 2000, 39(3):585–589.

291. Lipoprotein lipase mediates the uptake of glycated LDL in fibroblasts, endothelial cells, and macrophages, Robert Zimmermann.

292. Glycation of very low density lipoprotein from rat plasma impairs its catabolism, Mamo JC, Diabetologia, June 1990, 33(6):339-45.

293. Modification of low density lipoprotein by advanced glycation end products contributes to the dyslipidemia of diabetes and renal insufficiency, Bucala R, Proc Natl Acad Sei USA, September 27, 1994, 91(20):9441-5.

294. Glycation of very low density lipoprotein from rat plasma impairs its catabolism, Mamo JC, Diabetologia, June 1990, 33(6):339-45. Вывод, сделанный в исследовании: «Гликирование [налипание сахара на] ЛОНП, похоже, мешает липолизу [разгрузке] его триглицерида. Возможно, это объясняет задержку в переработке гликированных триглицеридов ЛОНП in vivo».

295. Thermally oxidized dietary fats increase the susceptibility of rat LDL to lipid peroxidation but not their uptake by macrophages, Eder K, / Nutr, September 2003, 133(9):2830-7.

296. Myeloperoxidase and plaque vulnerability, Hazen SL, Arteriosclerosis, Thrombosis, and Vascular Biology, 2004, 24:1143.

297. Oxidation-reduction controls fetal hypoplastic lung growth, Fisher JC, / Surg Res, August 2002, 106(2):287-91.

298. Intake of high levels of vitamin A and polyunsaturated fatty acids during different developmental periods modifies the expression of morphogenesis genes in European sea bass (Dicentrarchus labrax), Villeneuve LA, Br J Nutr, April 2006, 95(4):677-87.

299. Neural tube defects and maternal biomarkers of folate, homocysteine, and glutathione metabolism, Zhao W, Birth Defects Res A Clin Mol Teratol, April 2006, 76(4):230-6.

300. Congenital heart defects and maternal biomarkers of oxidative stress, Hobbs CA, Am J Clin Nutr, September 2005, 82(3):598–604.

301. A reduction state potentiates the glucocorticoid response through receptor protein stabilization, Kitugawa H, Genes Cells, November 2007, 12(ll):1281-7.

302. Trends in serum lipids and lipoproteins of adults, 1960–2002, Carrol MD, vol. 294, no. 14, October 12, 2005.

303. Application of new cholesterol guidelines to a population-based sample, Pencina MJ1, N Engl J Med, April 10, 2014, 370(15):1422-31, doi: 10.1056/NEJMoal315665, epub March 2014.

304. On the Take: How Medicines Complicity with Big Business Can Endanger Your Health, Jerome P. Kassirer, Oxford University Press, 2005.

305. Overdosed America: The Broken Promise of American Medicine, John Abramson, Harper Collins, 2004.

306. Adverse birth outcomes among mothers with low serum cholesterol, Edison RJ, Pediatrics, vol. 120, no. 4, October 2007, pp. 723–733.

Глава 8

307. The stomach as a bioreactor: dietary lipid peroxidation in the gastric fluid and the effects of plant-derived antioxidants, Free Radical Biology and Medicine, vol. 31, issue 11, December 1, 2001, pp. 1388–1395.

308. Protective effect of oleic acid against acute gastric mucosal lesions induced by ischemia-reperfusion in rat, Saudi Journal of Gastroenterology, 2007, vol. 13, issue 1, p. 17.

309. Lipid peroxidation by “free” iron ions and myoglobin as affected by dietary antioxidants in simulated gastric fluids, / Agric Food Chem, May 4, 2005, 53(9):3383-90, www.ncbi.nlm.nih.gov/ pubmed/15853376

310. Linoleic acid, a dietary n-6 polyunsaturated fatty acid, and the aetiology of ulcerative colitis: a nested case-control study within a European prospective cohort study, Gut, December 2009, 58(12): 1606-11, doi 10.1136/gut.2008.169078, epub July 2009.

311. “Owing to the fact that DHA has a higher number of double bonds compared with AA, DHA is more susceptible to free radical-mediated oxidation,” from page 34 of Omega-3 Fatty Acids in Brain and Neurological Health, edited by Ronald Ross Watson, Fabien De Meester, Academic Press, 2014, Elsevier.

312. Oxidation of marine omega-3 supplements and human health, Benjamin В Albert, 1, David Cameron-Smith, 1, Paul L Hofman, 1, 2, and Wayne S Outfield, 1,2, BioMed Research International, vol. 2013, 2013, article ID 464921, 8 pages, www.dx.doi.org/10.1155/2013/464921

313. Formation of malondialdehyde (MDA), 4-hydroxy-2-hexenal (HHE) and 4-hydroxy-2-nonenal (HNE) in fish and fish oil during dynamic gastrointestinal in vitro digestion, Food Fund, February 17, 2016, 7(2):1176-87.

314. Association of proton pump inhibitors with risk of dementia, JAMA Neurol, published online February 15, 2016.

315. Brain Maker: The Power of Gut Microbes to Heal and Protect Your Brain-For Life, David Perlmutter, Little, Brown, April 28, 2015, from Gut: The Inside Story of Our Body’s Most Underrated Organ, Greystone Books.

316. Obese-type gut microbiota induce neurobehavioral changes in the absence of obesity, Bruce-Keller AJ, Biol Psychiatry, April 1, 2015, 77(7):607-15.

317. Там же.

318. Там же.

319. Effect of intestinal microbial ecology on the developing brain, Douglas-Escobar M, JAMA Pediatr, April 2013, 167(4):374-9.

320. Aust NZ J Psychiatry, December 2011, 45(12): 1023-5, Probiotics in the treatment of depression: science or science fiction? Dinan TG.

321. Intestinal microbiota, probiotics and mental health, from Metchnikoff to modern advances, part III, Convergence toward clinical trials, Alison C Bested, Gut Pathog, 2013, 5: 4.

322. The role of gut microbiota in the gut-brain axis: current challenges and perspectives, Chen X, Protein Cell, June 2013, 4(6):403-14.

323. Obese-type gut microbiota induce neurobehavioral changes in the absence of obesity, Bruce-Keller AJ, Biol Psychiatry, April 1, 2015, 77(7):607-15.

324. Ингредиенты для питания контрольной группы: file:///Users/cateshanahan/Down-loads/product_data_D 12450B.pdf, ингредиенты для питания группы с большим содержанием жира: file:///Users/cateshanahan/Downloads/product_data_D 1245l.pdf.

325. Oxidation stability and fatty acid composition of selected storage and structural lipids: influence of different high fat diet compositions. The combination of sunflower oil and lard resulted in the highest amount of oxidation, compared to butter, lard, and partially hydrogenated oil, Nahrung, 1988, 32(4):365-74.

326. Mitochondrial formation of reactive oxygen species, Julyio F Turrens, Journal of Physiology, October 2003.

327. Chronic n-3 polyunsaturated fatty acid deficiency alters dopamine vesicle density in the rat frontal cortex, Luc Zimmer, Neuroscience Letters 284,1–2 (2000): 25–28.

328. Curr Neuropharmacol, March 2014, 12(2): 140–147, Oxidative stress and psychological disorders: «Мозг, обладающий способностью поглощать большие объемы кислорода и вырабатывать свободные радикалы, считается особенно уязвимым для окислительного стресса». www.ncbi.nlm.nih.gov/pmc/articles/PMC3964745/

329. Curr Neuropharmacol, March 2009, 7(1): 65–74, Oxidative stress and neuro degenerative diseases: a review of upstream and downstream antioxidant therapeutic options.

330. Curr Neuropharmacol, March 2014, 12(2): 140–147, Oxidative stress and psychological disorders.

331. Toxicity of oxidized fats II: tissue levels of lipid peroxides in rats fed a thermally oxidized corn oil diet. «В мозге содержится более высокий уровень липидпероксидов после употребления в пищу масла, несколько раз окисленного нагреванием».

332. Peroxyl radicals: inductors of neurodegenerative and other inflammatory diseases, their origin and how they transform cholesterol, phospholipids, plasmalogens, polyunsaturated fatty acids, sugars, and proteins into deleterious products, Spiteller G, Free Radic Biol Med, August 1, 2006, 41(3):362-87.

333. Triacylglycerol oxidation in pig lipoproteins after a diet rich in oxidized sunflower seed oil, Lipids, 40, 437–444, May 2005. «Исследования показывают, что окисленные липиды в пище повышают уровень окисленности хиломикронов и ЛОНП. Кроме окисленных ЛПНП, играющих главную роль в атерогенезе, окисленные хиломикроны и их остатки тоже являются потенциально атерогенными. Окисление хиломикронов создает частицы, которые могут служить субстратом для рецепторов-уборщиков. Хиломикроны и их остатки могут ассоциироваться с артериальной тканью даже эффективнее, чем ЛПНП».

334. Effect of dietary oils on lipid peroxidation and on antioxidant parameters of rat plasma and lipoprotein fractions, C Scaccini, 1. M. Nardini,’ M. DAquino, V. Gentili, M. Di Felice, and G. Tomassit, Istituto Nazionale della Nutrizione, Rome, Italy, and Universith della Tuscia, Viterbo, Italy, Journal of Lipid Research, vol. 33, 1992, 627–633. «Употребление в пищу мононенасыщенных жиров вместо полиненасыщенных вырабатывает частицы липопротеинов, обладающие заметной сопротивляемостью к окислительной модификации. С другой стороны, антиоксидантные вещества в пище влияют на сопротивление липопротеинов переокислению».

335. Lipidomics and Н2180 labeling techniques reveal increased remodeling of DHA-contain-ing membrane phospholipids associated with abnormal locomotor responses in a-tocopherol deficient zebrafish (danio rerio) embryos, Redox Biology, vol. 8, August 2016, pp. 165–174.

336. Associations between the antioxidant network and emotional intelligence: a preliminary study, Pesce, Mirko et al, Vladimir N Uversky (editor), PLoS ONE 9.7 (2014): el01247, PMC, Web, April 10, 2016.

337. The adult brain makes new neurons, and effortful learning keeps them alive, Tracy J Shors, Current Directions in Psychological Science, October 2014, vol. 23, no. 5311-318.

338. Influence of dietary thermally oxidized soybean oil on the oxidative status of rats of different ages, Ann Nutr Metab, 1990, 34(4):221-31.

339. Biological studies on the protective role of artichoke and green pepper against potential toxic effect of thermally oxidized oil in mice, Arab J, Biotech, vol. 12, no. 1, January 2009, 27–40, http://www.acgssr.org/BioTechnology/Vol.12NlJanuary2009_files/abstract/003.pdf

340. 2015 Gallup Poll (самый большой из опросов на данную тему): One in five Americans include gluten-free foods in diet, ссылка открыта 6 апреля 2016 года; www.gallup.com/poll/184307/ one- five – americans – include – glutenfree- fo о ds – diet, aspx

341. Опрос 2012 года, проведенный NPD Group, ссылка открыта 6 апреля 2016 года; https://www.npd.com/wps/portal/npd/us/news/press-releases/percentage-of-us-adults-trying-to-cut-down-or-avoid-gluten-in-their-dietsreaches-new-high-in-2013-reports-npd/

342. The prevalence of celiac disease in average-risk and at-risk Western European populations: a systematic review, Dube, C et al, Gastroenterology 128, suppl. 1, S57-S67 (2005).

343. Non-celiac gluten sensitivity: the new frontier of gluten related disorders, Carlo Catassi, Nutrients, October 2013, 5(10): 3839–3853.

344. Food allergy among U.S. children: trends in prevalence and hospitalizations, NCHS Data Brief No. 10, October 2008.

345. Effects of dietary oxidized frying oil on immune responses of spleen cells in rats, Reaeawh, W, Nutrition, 17, no. 4.

346. www.fmri.ucsd.edu/Research/whatisfmri.html

347. Там же.

348. Role of nitric oxide and acetylcholine in neocortical hyperemia elicited by basal forebrain stimulation: evidence for an involvement of endothelial nitric oxide, 1995, Neuroscience 69,1195–1204.

349. Там же.

350. Endothelial nitric oxide: protector of a healthy mind, Zvonimir S. Katusic and Susan A. Austin, Eur Heart J, April 7, 2014, 35(14): 888–894, www-ncbi-nlm-nih-gov.prx.hml.org/pmc/ articles/PMC3977136/

351. Essential role of endothelial nitric oxide synthase for mobilization of stem and progenitor cells, Aicher A, Heeschen C, Mildner-Rihm C, Urbich C, Ihling C, Technau-filling K, Leiher AM, Dimmeler S, Nat Med, 2003, 9:1370–1376.

352. Neurovascular regulation in the normal brain and in Alzheimer’s disease, Iadecola C, Nat Rev Neurosci, May 2004, 5(5):347-60.

353. Endothelial nitric oxide: protector of a healthy mind, Zvonimir S Katusic and Susan A Austin, Eur Heart J, April 7, 2014, 35(14): 888–894, www,ncbi-nlm-nih-gov.prx.hml.org/pmc/ articles/PMC3977136/

354. Tonic and phasic nitric oxide signals in hippocampal long-term potentiation, Hopper RA, Garthwaite J, / Neurosci, 20;26:11513-11521.

355. Endothelial function and oxidative stress in cardiovascular diseases, Circ J 2009; 73: 411–418.

356. Associations between the antioxidant network and emotional intelligence: a preliminary study, PLoS One, 2014; 9(7): el01247, www.ncbi.nlm.nih.gov/pmc/articles/PMC4077755/.

357. Cognitive cost as dynamic allocation of energetic resources, Front Neurosci, 2015, 9: 289, www.ncbi.nlm.nih.gov/pmc/articles/PMC4547044/

358. Impaired endothelial function following a meal rich in used cooking fat, Michael JA Williams, Journal of the American College of Cardiology, vol. 33, issue 4, March 15, 1999, pp. 1050–1055.

359. Effects of repeated heating of cooking oils on antioxidant content and endothelial function (review), Austin Journal of Pharmacology and Therapeutics, April 07, 2015.

360. Migraine, headache, and the risk of stroke in women: a prospective study, Kurth T, Slomke MA, Käse CS, et al, Neurology, 2005, 64:1020-6.

361. Migraine and ischaemic heart disease and stroke: potential mechanisms and treatment implications, Tietjen GE, Cephalalgia, 2007, 27:981-7.

362. Migraine aura pathophysiology: the role of blood vessels and microembolisation, Turgay Dalkara, Lancet Neurol, March 2010, 9(3): 309–317.

363. Arginine-nitric oxide pathway and cerebrovascular regulation in cortical spreading depression, Am J Physiol, July 1995, 269(1 pt. 2):H23-9.

364. Migraine aura without headache pathogenesis and pathophysiology, MedMerits.com, article section 6 of 14, Shih-Pin Chen, http://www.medmerits.com/index.php/article/migraineau-r awithoutheadache/P 5.

365. Arginine-nitric oxide pathway and cerebrovascular regulation in cortical spreading depression, Am J Physiol, July 1995, 269(1 pt. 2):H23-9.

366. Migraine aura without headache pathogenesis and pathophysiology, MedMerits.com, article section 6 of 14, Shih-Pin Chen, http://www.medmerits.com/index.php/article/migraineau-rawithoutheadache/P5.

367. Perfusion-weighted imaging defects during spontaneous migrainous aura, Ann Neurol, January 1998, 43(1):25–31.

368. Migraine aura without headache pathogenesis and pathophysiology, MedMerits.com, article section 6 of 14, Shih-Pin Chen, http://www.medmerits.com/index.php/article/migraineau-rawithoutheadache/P5.

369. Structural brain changes in migraine, JAMA, November 14, 2012; 308(18): 1889–1897, www.ncbi-nlmnih-gov.prx.hml.org/pmc/articles/PMC3633206/

370. Там же.

371. Oxidative stress and the aging brain: from theory to prevention, Gemma C, Vila J, Bach-stetter A, et al, Riddle DR (editor); Brain Aging: Models, Methods, and Mechanisms, Chapter 15, Boca Raton, FL, CRC Press/Taylor and Francis, 2007, www.ncbi.nlm.nih.gov/books/NBK3869/

372. Peroxyl radicals: inductors of neuro degenerative and other inflammatory diseases, their origin and how they transform cholesterol, phospholipids, plasmalogens, polyunsaturated fatty acids, sugars, and proteins into deleterious products, Spiteller G, Free Radical Biology and Medicine, 41, 2006, pp. 362–387.

373. Linoleic acid peroxidation – the dominant lipid peroxidation process in low density lipoprotein – and its relationship to chronic diseases (review), Spiteller G, Chemistry and Physics of lipids, 95 (1998) pp. 105–162.

374. Concussions, and the NFL: how one doctor changed football forever, Laskas Jeanne Marie, Bennet Omalu, September 15, 2009, www.gq.com/story/nfl-players-brain-dementia-study-memory-concussions

375. Там же.

376. Determination of lipid oxidation products in vegetable oils and marine omega-3 supplements, Food NutrRes, 2011, 55: 10, www.ncbi-nlm-nih-gov.prx.hml.org/pmc/articles/PMC3118035/

377. Molecular aspects of medicine, vol. 24, issues 4–5, pp. 147–314, August-October 2003, 4 – Hydroxynonenal: a lipid degradation product provided with cell regulatory functions.

378. Involvement of microtubule integrity in memory impairment caused by colchicine, Pharmacology Biochemistry and Behavior, vol. 71, issues 1–2, January-February 2002, pp. 119–138.

379. 4-Hydroxy-2-nonenal, a reactive product of lipid peroxidation, and neuro degenerative diseases: a toxic combination illuminated by redox proteomics studies, Antioxid Redox Signal, December 1, 2012, 17(11): 1590-160.

380. Там же.

381. Neuronal microtubules: when the MAP is the roadblock, Trends in Cell Biology, vol. 15, issue 4, April 2005, pp. 183–187.

382. 4-Hydroxy-2-nonenal, a reactive product of lipid peroxidation, and neuro degenerative diseases: a toxic combination illuminated by redox proteomics studies, Antioxid Redox Signal, December 1, 2012, 17(11): 1590-160.

383. MRI vs. clinical predictors of Alzheimer disease in mild cognitive impairment, Neurology, January 15, 2008, 70(3):191-9, vol. trie.

384. Neuron number and size in prefrontal cortex of children with autism, Courchesne E, Mouton PR, Calhoun ME, et al, JAMA, 2011, 306(18):2001–2010.

385. Local brain connectivity across development in autism spectrum disorder: a cross-sectional investigation, Autism Res, January 2016, 9(l):43–54, doi 10.1002/aur.l494, epub June 2015.

386. Dr. Anthony Bailey of the University of British Columbia presents Neurobiology of autism spectrum disorders, a care-ID web presentation, from Care ID YouTube Channel, accessed online on April 11, 2016, at www.youtube.com/watch?v=0IudE9OrIOE; minute 27:00 shows novel columns in the brainstem.

387. Using human pluripotent stem cells to model autism spectrum disorders, Carol Marchetto, YouTube video presentation online from the Salk Institute YouTube Channel, accessed online on April 11, 2016 at www.youtube.com/watch?v=eB9JonYylxo, minute 13:00.

388. Patches of disorganization in the neocortex of children with autism, Stoner R, Chow ML, Boyle MP, Sunkin SM, Mouton PR, Roy S, Wynshaw-Boris A, Colamarino SA, Lein ES, Courchesne E. NEJM, March 27, 2014.

389. Non-verbal girl with autism speaks through her computer, 20/20 ABC News Story reported by John Stossel, accessible via STAR Center (Sensory Therapies and Research Center) YouTube Channel, accessed on April 11, 2016 at www.youtube.com/watch?v=xMBzJleeOno.

390. Там же.

391. Schizophrenic reaction, childhood type, DSM I, 1952, entry 000-x28, открыто по ссылке 5 марта 2016 года: www.unstrange.com/dsml.html

392. Diagnostic criteria for infantile autism, DSM III, 1980, открыто по ссылке 5 марта 2016 года: www.unstrange.com/dsml.html

393. Открыто по ссылке 5 марта 2016 года: www.cdc.gov/ncbddd/autism/addm.html

394. Combined vaccines are like a sudden onslaught to the body’s immune system’: parental concerns about vaccine overload’ and ‘immune-vulnerability, Hilton S, Petticrew M, Hunt K, Vaccine. 2006;24(20):4321-7.

395. Maternal smoking and autism spectrum disorder: a meta-analysis, Rosen BN, Lee BK, Lee NL, Yang Y, Burstyn I.

396. In utero exposure to selective serotonin reuptake inhibitors and risk for autism spectrum disorder, Gidaya NB, Lee BK, Burstyn I, Yudell M, Mortensen EL, Newschaffer CJ, / Autism Dev Disord, October 2014, 44(10):2558-67.

397. Reduced prefrontal dopaminergic activity in valproic acid-treated mouse autism model, Нага Y, Takuma K, Takano E, Katashiba K, Taruta A, Higashino K, Hashimoto H, Ago Y, Matsuda T, Behav Brain Res, August 1, 2015, 289:39–47.

398. Current research on methamphetamine-induced neurotoxicity: animal models of monoamine disruption (review), Kita T, Wagner GC, Nakashima T, / Pharmacol Sei, July 2003, 92(3):178-95

399. Prenatal exposure to a common organophosphate insecticide delays motor development in a mouse model of idiopathic autism, De Felice A, Scattoni ML, Ricceri L, Calamandrei G, PLoS One,Mar 24, 2015, 10(3):e0121663.

400. Neurodevelopmental disorders and prenatal residential proximity to agricultural pesticides: the CHARGE study, Shelton JF, Geraghty EM, Tancredi DJ, Delwiche LD, Schmidt RJ, Ritz В, Hansen RL, Hertz-Picciotto I, Environ Health Perspect, October 2014, 122(10): 1103-9.

401. Early exposure to bisphenol A alters neuron and glia number in the rat prefrontal cortex of adult males, but not females, Neuroscience, October 24, 2014, 279:122-31, doi 10.1016/J Neuroscience, 2014.08.038, epub 2014.

402. Childhood autism and associated comorbidities, Brain and Development, June 2007, vol. 29, issue 5, pp. 257–272.

403. Mercury exposure and child development outcomes, Davidson PW, Myers GJ, Weiss B, Pediatrics, 2004, 113(4 suppl): 1023-9.

404. Sleep spindles, mobile phones, lucid dreaming and sleep in Parkinsons disease and autism spectrum disorders, Dijk DJ, / Sleep Res, December 2012, 21(6):601-2.

405. Risk of autism spectrum disorders in children born after assisted conception: a population-based follow-up study, Hvidtjorn D, Grove J, Schendel D, Schieve LA, Svaerke C, Ernst E, Ihorsen P, / Epidemiol Community Health, June 2011, 65(6):497–502.

406. Perinatal factors and the development of autism: a population study, Arch Gen Psychiatry, June 2004, 61(6):618-27.

407. Out of time: a possible link between mirror neurons, autism and electromagnetic radiation, Thornton IM, Med Hypotheses, 2006, 67(2):378-82.

408. Polybrominated diphenyl ether (PBDE) flame retardants as potential autism risk factors (review), Messer A, Physiol Behav, June 1,2010, 100(3):245-9, doi 10.1016/j.physbeh.2010.01.011, epub January 2010.

409. Antenatal ultrasound and risk of autism spectrum disorders. Grether JK, Li SX, Yoshida CK, Croen LA. / Autism Dev Disord. Feb 2010;40(2):238-45.

410. Autism and attention-deficit/hyperactivity disorder among individuals with a family history of alcohol use disorders, Sundquist J, Sundquist K, Ji J, Elife, August 2014.

Глава 9

411. Med Hypotheses, August 2013, 81(2):251-2, doi 10.1016/j.mehy.2013.04.037, epub May 2013, May 21.Iatrogenic autism.Hahr JY1.

412. Influence of candidate polymorphisms on the dipeptidyl peptidase IV and p-opioid receptor genes expression in aspect of the ß-casomorphin-7 modulation functions in autism, Cieslinska A, Sienkiewicz, Szlapka E, Wasilewska J, Fiedorowicz E, Chwala B, Moszynska-Dumara M, Cieslinski T, Bukalo M, Kostyra E, Peptides, March 2015, pp. 6–11.

413. Soy infant formula may be associated with autistic behaviors, Westmark CJ, Autism Open Access, November 2013, 18;3, pp: 20727.

414. The relationship of autism and gluten, Buie T, Clin Eher, May 2013, 35(5):578-83.

415. A review of dietary interventions in autism, Annals of Clinical Psychiatry, 2009; 21(4):237-

247.

416. Methods to create thermally oxidized lipids and comparison of analytical procedures to characterize peroxidation, / Anim Sei, July 2014, 92(7):2950-9, doi 10.2527/jas.2012–5708, epub May 2014.

417. Данные за 1994 год показывают, что каждый житель США в среднем ежегодно употребляет 25,1 кг растительного масла, что соответствует 618 калориям в день. Данные из таблиц на сайте USDA говорят, что в 2014 году потребление растительного масла выросло на 170 процентов по сравнению с 1995 годом. Если предполагать, что в 1994 и 1995 году масла употребили примерно одинаково, то при подсчете данных за 2014 год мы получаем, что каждый житель США в среднем потребляет 1000 калорий в день из растительных масел. Калорийность рациона каждого отдельного американца, естественно, может быть очень разной, но, по оценкам 2015 года, среднестатистический американец съедает 3600 калорий в день, а худые американцы – от 1700 до 3000 калорий в зависимости от того, насколько они активны. Оценки для потребителей, заботящихся о своем здоровье, основаны на личном опыте: большинство таких потребителей готовят дома, поэтому меньше подвергаются воздействию растительных масел. Источники: данные 1995 года – из таблицы 6 в статье Polyunsaturated fatty acids in the food chain in the United States, Am J Clin Nutr, January, 2000, vol. 71, no. 1, pp. 179S-188. Данные 2014 года – из таблиц по адресу www.ers.usda.gov/data-products/ oil-crops-yearbook.aspx.

418. Costs of autism spectrum disorders in the United Kingdom and the United States, Bue-scher AS, Cidav Z, Knapp M, Mandell DS, JAMA Pediatr, 2014, 168(8):721–728, doilO.lOOl/jama-pediatrics.2014.210.

419. Chemistry and biology of DNA containing 1, N2-deoxyguanosine adducts of the a,ß-unsaturated aldehydes acrolein, crotonaldehyde, and 4-hydroxynonenal, Chem Res Toxicol, May 18, 2009, 22(5): 759–778.

420. Mutational specificity of y-radiation-induced g-thymine and thymine-guanine intrastrand cross-links in mammalian cells and translesion synthesis past the guanine-thymine lesion by human DNA polymerase, Biochemistry, August 5, 2008; 47(31): 8070–8079.

421. Rates of spontaneous mutation, Drake JW, Charlesworth В, Charlesworth D, Crow JF, Genetics, April 1998, 148 (4): 1667-86.

422. Mutagenic/recombinogenic effects of four lipid peroxidation products in Drosophila. Food Chem Toxicol March 2013, 53:ch221-7, doi 10.1016/j.fct.2012.11.0,3, epub December 2012.

423. Dietary oxidized n-3 PUFA induce oxidative stress and inflammation: role of intestinal absorption of 4-HHE and reactivity in intestinal cells, / Lipid Res, October 2012, 53(10):2069-80, doi 10.1194/jlr.M026179, epub August 2012.

424. Role of glutathione in the radiation response of mammalian cells in vitro and in vivo, Bump EA, Brown JM, Pharmacol Ther, 1990, 47(1):117-36.

425. Glutathione modifies the oxidation products of 2’-deoxyguanosine by singlet molecular oxygen, Peres PS, Valerio A, Cadena SM, Winnischofer SM, Scalfo AC, Di Mascio P, Martinez GR, Arch Biochem Biophys, November 15, 2015, 586:33–44, doi 10.1016/j.abb.2015.09.020, epub September 2015.

426. Unequivocal demonstration that malondialdehyde is a mutagen, Carcinogenesis, 1983, 4(3):331-3.

427. Oxy radicals, lipid peroxidation and DNA damage, Toxicology, December 27, 2002, 181–182:219-22.

428. Там же.

429. Malondialdehyde, a major endogenous lipid peroxidation product, sensitizes human cells to UV- and BPDE-induced killing and mutagenesis through inhibition of nucleotide excision repair, Mutat Res, October 10, 2006, 601(l-2):125-36, epub July 2006.

430. Trans-4-hydroxy-2-nonenal inhibits nucleotide excision repair in human cells: a possible mechanism for lipid peroxidation-induced carcinogenesis, Proc Natl Acad Sei USA, June 2004, 8;101(23):8598-602.

431. Global increases in both common and rare copy number load associated with autism, Hum Mol Genet, July 15, 2013, 22(14): 2870–2880.

432. Global increases in both common and rare copy number load associated with autism, Hum Mol Genet, July 15, 2013, 22(14): 2870–2880. В статье в основном обсуждается категория мутаций, которая называется «перегружающее число копий»: длинные участки ДНК либо присутствуют в ненормально большом количестве, либо копия гена вообще отсутствует. В этом исследовании обнаружили, что дупликаций стало больше в 7,7 раз, а делеций – в 2,3 раза.

433. Global increases in both common and rare copy number load associated with autism, Hum Mol Genet, July 15, 2013, 22(14): 2870–2880.413, MMWR CDC Surveill Summ, December 1990, 39(4): 19–23, Temporal trends in the prevalence of congenital malformations at birth based on the birth defects monitoring program, Edmonds LD, United States, 1979–1987.

434. Global increases in both common and rare copy number load associated with autism, Hum Mol Genet, July 15, 2013, 22(14): 2870–2880.

435. Global increases in both common and rare copy number load associated with autism, Hum Mol Genet, July 15, 2013, 22(14): 2870–2880.

436. The association between congenital anomalies and autism spectrum disorders in a Finnish national birth cohort, Dev Med Child Neurol, January 2015, 57(1): 75–80.

437. Minor malformations and physical measurements in autism: data from Nova Scotia, Teratology, 55:319–325 (1997).

438. MMWR CDC Surveill Summ. 1990 Dec;39(4):19–23). Temporal trends in the prevalence of congenital malformations at birth based on the birthdefects monitoring program, United States, 1979–1987. Edmonds LD. (Да, это самый новый доклад. Судя по всему, CDC посчитал эту статистику недостаточно пугающей, чтобы проверить, не продолжается ли тенденция.)

439. Prevalence of autism spectrum disorder among children aged eight years – autism and developmental disabilities monitoring network, eleven sites, United States, 2010, Surveillance Summaries, March 28, 2014/63(SS02); 1-21.

440. Advancing paternal age and risk of autism: new evidence from a population-based study and a meta-analysis of epidemiological studies, Mol Psychiatry, December 2011, (12): 1203-12.

441. Тростниковый сахар: 72 кг на человека в год. Кукурузный сироп с фруктозой: 20 кг на человека в год.

442. Maternal obesity and risk for birth defects, Watkins ML, Pediatrics, vol. Ill, no. 5, May 2003, pp. 1152–1158.

443. Fasting glucose in acute myocardial infarction, incremental value for long-term mortality and relationship with left ventricular systolic function, Aronson D, Diabetes Care, 30:960–966, 2007.

444. IGT and IFG, time for revision? K. Borch-Johnsen, Diabetic Medicine, vol. 19, issue 9, September 2002, pp. 707–707.

445. The modern nutritional diseases, Ottoboni F, 2002: «Эпидемиологические исследования человеческих популяций показали, что атеросклеротические сердечно-сосудистые заболевания чаще встречались в богатых обществах и среди высших социоэкономических классов. Эти исследования связывали повышенную заболеваемость с употреблением «роскошной еды», избыточным потреблением калорий, сладостями, сидячим образом жизни и стрессом».

446. Americas eating habits: changes and consequences, Frazao E (editor), Agriculture Information Bulletin No. (AIB750) 484, May 1999, Chapter 7: Trends in the US. food supply: 1970-97.

447. Insulin and glucagon modulate hepatic 3-hydroxy-3-methylglutaryl-со enzyme a reductase activity by affecting immunoreactive protein levels, G Ness, Journal of Biological Chemistry, 18 November 1994, 29168-72.

448. Restricted daily consumption of a highly palatable food (chocolate Ensure) alters striatal enkephalin gene expression, Kelley AE, European Journal of Neuroscience, 18 (9), pp. 2592–2598. Авторы делают вывод: «постоянное потребление награждающей, богатой энергией пищи приводит к нейроадаптации в когнитивно-мотивационных цепях». Многочисленные похожие исследования поддерживают идею, что у животных с привыканием к сахару происходят в мозге те же химические изменения, что и при привыкании к опиатам.

449. Routine sucrose analgesia, during the first week of life in neonates younger than thirty-one weeks’ postconceptional age, Johnston CC, Pediatrics, vol. 110, no. 3, September 2002, pp. 523–528.

450. Там же.

451. Там же.

452. Central insulin resistance as a trigger for sporadic Alzheimer-like pathology: an experimental approach review, Salkovic-Petrisic M, Hoyer S, / Neural Transm Suppl, 2007, (72):217-33.

453. Aging of the brain (review), Mech Aging Dev, Anderton BH, April 2002, 123(7):811-7.

454. Taste preference for sweetness in urban and rural populations in Iraq, Jamel HA, / Dent Res, 75(11): 1879–1884, November 1996.

455. Pediasure brand nutritional supplement label information, открыто по ссылке 22 августа 2007 года: www.pediasure.com/pedia_info.a.px

456. Observations on the economic adulteration of high value food products, Fairchild GF, Journal of Food Distribution Research, vol. 32, no. 2, July 2003, pp. 38–45.

457. Список ингредиентов на упаковке Kelloggs Raisin Bran Crunch.

458. Fructose and non-fructose sugar intakes in the US population and their associations with indicators of metabolic syndrome, Sam Sun et al, Food and Chemical Toxicology, 49,11 (2011): 2874–2882.

459. Dietary fructose consumption among US children and adults: the third national health and nutrition examination survey, Miriam Vos et al, Medscape J Med, 10,7 (2008) 160.

460. The Cambridge World History of Food, Cambridge University Press, 2000, p. 1210.

461. Там же.

Глава 10

462. Dietary advanced glycation endproducts (AGEs) and their health effects – PRO, Sebekovä K, Mol Nutr Food Res, September 2007, 51(9): 1079-84.

463. Methylglyoxal in food and living organisms (review), Nemet I, Mol Nutr Food Res,December 2006, 50(12):1105-17.

464. Multidimensional scaling of ferrous sulfate and basic tastes, Stevens D, Physiology and Behavior, 2006, vol. 87, no. 2, pp. 272–279.

465. Neural circuits for taste: excitation, inhibition, and synaptic plasticity in the rostral gustatory zone of the nucleus of the solitary tract, Bradley RM, Annals of the New York Academy of Sciences, 855 (1), 467–474.

466. Excitotoxins: the taste that kills, Russel Blaylock, Health Press, 1996.

467. Body composition of white tailed deer, Robbins C, J, Anim Sei, 1974, 38:871–876.

468. University of New Hampshire Cooperative Extension, открыто по ссылке 19 августа 2008 года: www.extension.unh.edu/news/feedeer.htm

469. The Journals of Samuel Hearne,S Hearne, 1768. «Двадцать второго июля мы встретили нескольких незнакомцев, вместе с которыми охотились на карибу, которых в то время было настолько много, что нам хватало мяса на каждый день, и часто мы убивали нескольких только ради языков, костного мозга и жира».

470. The Narrative ofCabeza De Vaca, Cabeza de Vaca, Älvar Nunez, translation of La Relacion by Rolena Adorno and Patrick Charles Pautz, University of Nebraska Press, 2003.

471. CD36 involvement in orosensory detection of dietary lipids, spontaneous fat preference, and digestive secretions, Laugusterette FJ, Clin Invest, 115:3177–3184, 2005.

472. Evidence for human orosensory (taste) sensitivity to free fatty acids, Chale-Rush A, Chem Senses, June 1, 2007, 32(5): 423–431.

473. Multiple routes of chemosensitivity to free fatty acids in humans, Chale-Rush A, Am J Physiol Gastrointest Liver Physiol, 292: G1206-G1212, 2007.

474. Seeds of deception, exposing industry and government lies about the safety of the genetically engineered foods you’re eating, Smith J, Yes Books, 2003, pp. 77-105.

475. Nutraceuticals as therapeutic agents in osteoarthritis: the role of glucosamine, chondroitin sulfate, and collagen hydrolysate, Deal CL, Rheumatic Disease Clinics of North America, vol. 25, issue 2, May 1, 1999, pp. 379–395.

476. Там же.

477. The heparin-binding (fibroblast) growth factor family of proteins, Burgess W, Annual Review of Biochemistry, vol. 58: 575–602, July 1989.

478. Сайт Stone Foundation for Arthritis Help and Research, открыто по ссылке 10 октября 2007 года: www.stoneclinic.com/jJanuaryews.htm

479. Determinants and implications of bone grease rendering: a Pacific Northwest example, Prince P, North American Archaeologist, vol. 28, no.l, 2007.

480. A new approach to identifying bone marrow and grease exploitation: why the “indeterminate” fragments should not be ignored, Outram AK, Journal of Archaeological Science,2001, 28, pp. 401–410.

481. The Ladies New Book Of Cookery: A Practical System for Private Families in Town and Country; With Directions for Carving and Arranging the Table for Parties, Etc., Also Preparations of Food for Invalids and for Children, Sara Hosepha Hale, New York, H Long and Brother, 1852, p. 93.

482. Замораживание на две недели при температуре -20 °C убивает паразитов.

483. Lets Cook It Right, Adelle Davis, Signet, 1970, p. 87.

484. USDA Agricultural Resource Service Nutrient Data Library, открыто по ссылке 23 декабря 2005 года, www.nal.usda.gov/fnic/foodcomp/search/

485. Перефразировано в НЕ Jacob, Six Thousand Years of Bread: Its Holy and Unholy History, Skyhorse, 2007, p. 26.

486. The Cambridge World History of Food, Cambridge Unviersity Press, 2000, p. 1474.

487. Wind, Water, Work: Ancient and Medieval Milling Technology, Adam Lucas, Brill Academic Publishers, 2005.

488. The gut flora as a forgotten organ, Shanahan F, EMBO reports 7, 7, 688–693, 2006.

489. Nutrition and colonic health: the critical role of the microbiota, O’keefe SJ, Curr Opin Gastroenterol, January 2008, 24(l):51–58.

490. Serum or plasma cartilage oligomeric matrix protein concentration as a diagnostic marker in pseudoachondroplasia: differential diagnosis of a family, A Cevik Tufan et al, Fur J Hum Genet, 15: 1023–1028.

491. The Cambridge World History of Food, Cambridge Unviersity Press, 2000, p. 1473.

492. Effects of soy protein and soybean isoflavones on thyroid function in healthy adults and hypothyroid patients: a review of the relevant literature, Messina M, Thyroid, March 2006, 16(3):249-58.

493. Infant feeding with soy formula milk: effects on puberty progression, reproductive function and testicular cell numbers in marmoset monkeys in adulthood, Tan KA, Hum Reprod, April 2006, (4):896–904.

494. Food Values Of Portions Commonly Used, Pennington J, Harper, 1989.

495. Quorum sensing: cell-to-cell communication in bacteria, Waters CM, Bassler BL, Annu Rev Cell Dev Biol, 21:319–346, 2005.

496. The gut flora as a forgotten organ, Shanahan F, EMBO reports 7, 7, 688–693, 2006.

497. Probiotics in human disease (review), Isolauri E, Am J Clin Nutr, June 2001, 73(6):1142S-1146S.

498. Commensal bacteria (normal microflora), mucosal immunity and chronic inflammatory and auto-immune diseases (review), Sokol D, Immunol Lett, May 15, 2004, 93(2–3):97-108.

499. Probiotics and their fermented food products are beneficial for health (review), Parvez S, / Appl Microbiol, Jun 2006, 100(6):1171-85.

500. Nutritional comparison of fresh, frozen, and canned fruits and vegetables, Executive Summary of the Department of Food Science and Technology, University of California Davis, Davis, CA, Rickman J, www.mealtime.org/uploadedFiles/Mealtime/Content/ucdavisstudyexecutivesummary.pdf

501. Whole wheat and white wheat flour – the mycobiota and potential mycotoxins, Weidenbörner M, Food Microbiology, vol. 17, issue 1, February 2000, pp. 103–107.

502. The impact of processing on the nutritional quality of food proteins, Meade S, Journal of AOAC International, 2005, vol. 88, no. 3, pp. 904–922.

503. Lets Have Healthy Children, Adelle Davis, Signet, 1972, p. 95.

504. Bio availability and bioconversion of carotenoids, Castenmiller JJM, Annual Review of Nutrition, vol. 18: 19–38, July 1998.

505. Mrs. Hills Southern Practical Cookery and Receipt Book, AP Hill, Damon Lee Fowler, University of South Carolina Press, 1872.

506. The apparent incidence of hip fracture in Europe: a study of national register sources, Johnel O, Osteoporosis International, vol. 2, no. 6, November 1992.

507. The Last Hours of Ancient Sunlight: The Fate of the World and What We Can Do Before Its Too Late, revised and updated, Thom Hartman, Broadway, 2004.

508. The Milk Book: The Milk of Human Kindness Is Not Pasteurized, William Campbell Douglass II, Rhino Publishing, 2005.

509. Continuous thermal processing of foods: pasteurization and Uht, Heppell NJ, Springer 2000, p. 194.

510. Dr. North and the Kansas City Newspaper war: public health advocacy collides with main street respectability, Kovarik B, paper presented at the Annual Meeting of the Association for Education in Journalism and Mass Communication (72nd, Washington, D.C., August 10–13, 1989, открыто по ссылке 27 декабря 2007 года: www.radford.edu/wkovarik/papers/aej98.html

511. The Milk Book: The Milk of Human Kindness Is Not Pasteurized, William Campbell Douglass II, Rhino Publishing, 2005.

512. Там же, p. 11.

513. Modifications in milk proteins induced by heat treatment and homogenization and their influence on susceptibility to proteolysis, Garcia-Risco MR, International Dairy Journal, 12 (2002) pp. 679–688.

514. Soluble, dialyzable and ionic calcium in raw and processed skim milk, whole milk and spinach, Reykdal O, Journal of Food Science, 56 3, pp. 864–866, 1991.

515. Calcium bio availability in human milk, cow milk and infant formulas – comparison between dialysis and solubility methods, Roig MJ, Food Chemistry, vol. 65, issue 3, pp. 353–357.

516. Carbonylation of milk powder proteins as a consequence of processing conditions, Francois Fenaille, Proteomics, vol. 5, issue 12, pp. 3097–3104.

517. Modifications in milk proteins induced by heat treatment and homogenization and their influence on susceptibility to proteolysis, Garcia-Risco MR, International Dairy Journal, 12 (2002) pp. 679–688.

518. Chemistry and Safety of Acrylamide in Food, Friedman M, p. 141, Springer, 2005.

519. Lancet, May 8, 1937, p. 1142.

520. Nutrition abstracts and reviews, Fischr RA and Bartlett S, October 1931, vol. 1, p. 224.

521. Dietary fat requirements in health and development, Thomas H Applewhite, American Oil Chemists Society, 1988, p. 30.

Глава 11

522. Jaenisch, R, Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals, Nature Genetics, 33, 245–254 (2003).

523. Orexins in the brain-gut axis, Kirchgessner AL, Endocrine Reviews, 23 (1): 1-15.

524. Adipose tissue as an endocrine organ, Prins JB, Best Practice and Research Clinical Endocrinology and Metabolism, 2002, vol. 16, no. 4, pp. 639–651.

525. Reduction in adiposity affects the extent of afferent projections to growth hormone-re-leasing hormone and somatostatin neurons and the degree of colocalization of neuropeptides in growth hormone-releasing hormone and somatostatin cells of the ovine hypothalamus, Javed Iqbal J, Endocrinology, vol. 146, no. 11, pp. 4776–4785.

526. Peroxisome proliferator-activated receptor {gamma} and adipose tissue – understanding obesity-related changes in regulation of lipid and glucose metabolism, Sharma AM, Journal of Clinical Endocrinology and Metabolism, vol. 92, no. 2, pp. 386–395.

527. Leptin-induced growth stimulation of breast cancer cells involves recruitment of histone acetyltransferases and mediator complex to CYCLEN D1 promoter via activation of stat 3, Saxena NK, /. Biol Chem, vol. 282, issue 18, pp. 13316-13325, May 4, 2007.

528. Effect of dietary trans fatty acids on the delta 5, delta 6 and delta 9 desaturases of rat liver microsomes in vivo, Mahfouz M, Acta Biol Med Ger, 1981, 40(12):1699–1705. «Это исследование показывает, что пищевые трансжирные кислоты дифференцированно встраиваются в микросомные липиды печени и работают как ингибиторы дельта-9 и дельта-6 десатураз. Дельта-6-десатураза считается ключевым ферментом, перерабатывающим незаменимые жирные кислоты в арахидоновую кислоту и простагландины. Это показывает, что присутствие трансжирных кислот в рационе может в определенной степени влиять на метаболизм незаменимых жирных кислот, мешая работе десатураз.

529. A defect in the activity of delta 6 and delta 5 desaturases may be a factor predisposing to the development of insulin resistance syndrome, Das UN, Prostaglandins, Leukotrienes and Essential Fatty Acids, vol. 72, issue 5, May 2005, pp. 343–350.

530. Regulation of stearoyl-CoA desaturase by polyunsaturated fatty acids and cholesterol, M Ntambi, September 1999, Journal of Lipid Research, 40, pp. 1549–1558.

531. Role of stearoyl-CoA desaturases in obesity and the metabolic syndrome, H E Popeijus, International Journal of Obesity, 32, 1076–1082, doi 10.1038/ijo.2008.55, published online April 22, 2008.

532. Interruption of triacylglycerol synthesis in the endoplasmic reticulum is the initiating event for saturated fatty acid-induced lipotoxicity in liver cells, Mantzaris, February 2011, 278(3):519-30, doi 10.1111/j. 1742–4658.2010.07972.x.

533. The significance of differences in fatty acid metabolism between obese and non-obese patients with non-alcoholic fatty liver disease, Nakamuta M, Int J Mol Med, November 2008, 22(5):663-7.

534. Liver mitochondrial dysfunction and oxidative stress in the pathogenesis of experimental nonalcoholic fatty liver disease, Oliveira CP, Braz J Med Biol Res, February 2006, 39(2): 189-94, epub February 2006.

535. Insulin resistance, inflammation, and non-alcoholic fatty liver disease, Tilg H, Trends Endocrinol Metab, October 15, 2008, epub prior to print.

536. Apoptosis in skeletal muscle myotubes is induced by ceramide and is positively related to insulin resistance, Turpin SM, Am J Physiol Endocrinol Metab, 291: El341-El350, 2006.

537. Weapons of lean body mass destruction: the role of ectopic lipids in the metabolic syndrome (review), Unger RH, Endocrinology, December 2003, 144(12):5159-65.

538. Prostaglandins, Chuck S. Bronson, Nova Publishers, 2006. p. 51.

539. Dietary fat intake and risk of type 2 diabetes in women, Salmeron J, American Journal of Clinical Nutrition, vol. 73, no. 6, pp. 1019–1026, June 2001.

540. Sex differences in lipid and glucose kinetics after ingestion of an acute oral fructose load, Tran C, Jacot Descombes D, Lecoultre V, Fielding BA, Carrel G, Le KA, Schneiter P, Bortolotti M, Frayn KN, Tappy L, Br J Nutr, 2010, 104:1139–1147.

541. Regulation of adipose cell number in man, Prins JB, Clin Sei, London, 1997, 92: 3-11.

542. Neural Innervation of White Adipose Tissue and the Control of Lipolysis, Bartness, Timothy J. et al, Frontiers in Neuroendocrinology, 35.4 (2014): 473–493.PMC, web, April 15, 2016.

543. The cellular plasticity of human adipocytes, Tbolpady SS, Annals of Plastic Surgery, vol. 54, no. 6, June 2005, pp. 651-6.

544. Transdifferentiation potential of human mesenchymal stem cells derived from bone marrow, Song L, FASEB Journal, vol. 18, June 2004, pp. 980-82.

545. Reversible transdifferentiation of secretory epithelial cells into adipocytes in the mammary gland, Morron M, PNAS, November 30, 2004, vol. 101, no. 48, pp. 16801-16806.

546. Identification of cartilage progenitor cells in the adult ear perichondrium: utilization for cartilage reconstruction, Togo T, Laboratory Investigation, 2006, 86, pp. 445–457.

547. The cellular plasticity of human adipocytes, Tbolpady SS, Annals of Plastic Surgery, vol. 54, no. 6, June 2005, pp. 651-56.

548. The Health Report, ABC Radio International transcript, July 9, 2007, presented by Norman Swain.

549. Insulin-resistant subjects have normal angiogenic response to aerobic exercise training in skeletal muscle, but not in adipose tissue, Walton RG, Physiol Rep, June 2015, 3(6), pii, el2415, doi 10.14814/phy2.12415.

550. Transdifferentiation potential of human mesenchymal stem cells derived from bone marrow, Song L, FASEB, vol. 18, June 2004, pp. 980-82.

551. Adipose cell apoptosis: death in the energy depot, A Sorisky, International Journal of Obesity, 2000, 24, suppl. 4, S3±S7.

552. In vivo dedifferentiation of adult adipose cells, Liao, Yunjun et al, Guillermo Lopez Lluch (editor), PLoS ONE 10.4 (2015): e0125254, PMC, web, April 15, 2016. «Адипоциты могут мощно экспрессировать маркеры эмбриональных стволовых клеток, например, October 4, Sox2, с-Мус и Nanog, после дедифференциации. Таким образом, они могут служить резервуаром плюрипотентных клеток в динамическом равновесии с клеточным составом конкретных органов и быть способными к фенотипической трансформации».

553. Changes in nerve cells of the nucleus basalis of Meynert in Alzheimer’s disease and their relationship to ageing and to the accumulation of lipofuscin pigment, Mann DM, Mech Ageing Dev, April-May 1984, 25(l-2):189–204.

554. Mechanisms of disease: is osteoporosis the obesity of bone? Rosen CJ, Nature Clinical Practice Rheumatology, 2006, 2, pp. 35–43.

555. Endocrinology of adipose tissue – an update, Fischer-Pozovsky P, Hormone Metabolism Research, May 2007, 36(5):314-21.

556. Exercise and the treatment of clinical depression in adults: recent findings and future directions, Brosse A, Sports Medicine, 32(12):741–760, 2002.

557. Beta-endorphin decreases fatigue and increases glucose uptake independently in normal and dystrophic mice, Kahn S, Muscle Nerve, April 2005, 31(4):481-6.

558. The differential contribution of tumour necrosis factor to thermal and mechanical hyperalgesia during chronic inflammation, Inglis JJ, Arthritis Res Ther, 2005, 7(4):R807-16, epub April 2005.

559. TNF-related weak inducer of apoptosis (TWEAK) is a potent skeletal muscle-wasting cytokine, Faseb J, June 2007, 21(8): 1857-69.

560. Aerobic exercise training increases brain volume in aging humans, Colcombe J, Journals of Gerontology Series A: Biological Sciences and Medical Sciences, 2006, 61:1166–1170.

561. Running increases cell proliferation and neurogenesis in the adult mouse dentate gyrus, Gage FH, Nat Neurosci, Mar 1999, 2(3):266-70.

562. Six sessions of sprint interval training increases muscle oxidative potential and cycle endurance capacity in humans, Burgomaster KA, / Appl Physiol, 98: 1985–1990, 2005.

563. Там же.

564. Plasma ghrelin is altered after maximal exercise in elite male rowers, Jürimäe J, Exp Biol Med, Maywood, July 2007, 232(7):904-9.

Глава 12

565. Update on food allergy, Sampson, H, Journal of Allergy and Clinical Immunology, vol. 113, issue 5, pp. 805–819.

566. Food allergy among U.S. children: trends in prevalence and hospitalizations, NCHS Data Brief No. 10, October 2008, Amy M. Branum, M.S.P.H. Figure 4, http://www.cdc.gov/nchs/products/ databriefs/db 10.htm

567. The relationship between lower extremity alighment char aether istics and anterior knee joint laxity, Shultz SJ, Sports Health 1, 1 (2009) 53-100.

568. Update on food allergy, Sampson H, Journal of Allergy and Clinical Immunology, vol. 113, issue 5, pp. 805–819.

569. Food allergy among U.S. children: trends in prevalence and hospitalizations, NCHS Data Brief No. 10, October 2008, Amy M. Branum, M.S.P.H. Figure 4, http://www.cdc.gov/nchs/products/ databriefs/db 10.htm

570. Facial soft tissue reconstruction: Thomas procedures in facial plastic surgery Gregory H, Branham Pmph USA, November 30, 2011, p. 17.

571. Glycation stress and photo-aging in skin, Masamitsu Ichihashi, Anti-Aging Medicine, 2011, vol. 8, no. 3, pp. 23–29.

572. Ageing and zonal variation in post-translational modification of collagen in normal human articular cartilage: the age-related increase in non-enzymatic glycation affects biomechanical properties of cartilage.

573. Ruud A. Bank, Biochemical Journal, February 15, 1998,330(1)345-351.

574. Diabetes, advanced glycation endproducts and vascular disease, Jean-Luc Wautier, Vase Med, May 1998, vol. 3, no. 2, pp. 131–137.

575. Role of advanced glycation end products in aging collagen, Gerontology, 1998, 44(4): 187-9.

576. Подробнее о том, как конечные продукты гликирования устанавливают перекрестные связи в коллагене, см. в главе 10.

577. Session 3: Joint Nutrition Society and Irish Nutrition and Dietetic Institute Symposium on ‘Nutrition and auto-immune disease PUFA, inflammatory processes and rheumatoid arthritis, Proc Nutr Soc, November 2008, 67(4):409-18.

578. Facial plastic surgery, scar management: prevention and treatment strategies, Chen, Margaret, Current Opinion in Otolaryngology and Head and Neck Surgery, August 2005, vol. 13, issue 4, pp. 242–247.

579. Metabolic fate of exogenous chondroitin sulfate in the experimental animal, Palmieri L, Arzneimittelforschung, March 1990, 40(3):319-23.

580. Proteoglycans and glycosaminoglycans, Silbert JE, in Biochemistry and Physiology of the Skin, Goldsmith LA (editor), Oxford University Press, 1983, pp. 448–461.

581. Anti-inflammatory activity of chondroitin sulfate, Ronca F, Osteoarthritis Cartilage, May 6, 1998, suppl. A:14–21.

582. Nutraceuticals as therapeutic agents in osteoarthritis: the role of glucosamine, chondroitin sulfate, and collagen hydrolysate, Deal CL, Rheumatic Disease Clinics of North America, vol. 25, issue 2, May 1, 1999.

583. The effect of concentrated bone broth as a dietary supplementation on bone healing in rabbits, Mahmood A, Aljumaily Department of Surgery, College of Medicine, University of Mosul, Ann Coll Med Mosul, 2011; 37 [1 and 2]: 42–47).

584. Cell death in cartilage, K. Kühn, Osteoarthritis and Cartilage, vol. 12, issue 1, January 2004, pp. 1-16.

585. The effect of hyaluronic acid on IL-lß-induced chondrocyte apoptosis in a rat model of osteoarthritis, Pang-Hu Zhou, Journal of Orthopaedic Research, December 2008, vol. 26, issue 12, pp. 1643–1648.

586. Cellulite and its treatment, Rawlings A, International Journal of Cosmetic Science, 2006, 28, pp. 175–190.

587. Mediators of Inflammation, vol. 2010 (2010), article ID 858176, 6 pages, Lipid mediators in acne, Monica Ottaviani.

588. Antioxidant activity, lipid peroxidation and skin diseases, what’s new, S Briganti, Journal of the European Academy of Dermatology and Venereology, vol. 17, issue 6, pp. 663–669, November 2003.

589. Inflammatory lipid mediators in common skin diseases, Kutlubay Z, Skinmed, February 1, 2016, l;14(l):23-7, eCollection 2016.

590. Inflammation in acne vulgaris, Guy F Webster, Journal of the American Academy of Dermatology, vol. 33, issue 2, part 1, August 1995, pp. 247–253.

591. Antioxidant activity, lipid peroxidation and skin diseases, what’s new, S Briganti, Journal of the European Academy of Dermatology and Venereology, vol. 17, issue 6, pp. 663–669, November 2003.

592. Inflammatory lipid mediators in common skin diseases, Kutlubay Z, Skinmed, February 1, 2016, l;14(l):23-7, eCollection 2016.

593. Dietary glycemic factors, insulin resistance, and adiponectin levels in acne vulgaris, (german AA, / Am Acad Dermatol, Apr 6, 2016, pii: SO 190-9622(16)01485-7.

594. Glycemic index, glycemic load: new evidence for a link with acne, Berra В J, Am Coll Nutr, August 2009, 28 suppl, 450S-454S.

595. Modern acne treatment, Zouboilis C, Aktuelle Dermatologie, 2003, vol. 29, no. 1–2, pp. 49–57.

596. Diet and acne redux, Valori Treloar, CNS Arch Dermatol, 2003, 139(7):941.

597. Flesh eating bacteria: a legacy of war and call for peace, Shanahan C, Pacific Journal, vol. 1, issue 1, 2007.

598. Kinetics of UV light-induced cyclobutane pyrimidine dimers in human skin in vivo: an immunohistochemical analysis of both epidermis and dermis, Katiyar S, Photochemistry and Photobiology, vol. 72, issue 6, pp. 788–793.

599. Ultraviolet irradiation increases matrix metalloproteinase-8 protein in human skin in vivo, GJ Fisher, Journal of Investigative Dermatology, vol. 117, issue 2, August 2001, pp. 219–226.

600. Vitamin D deficiency: a worldwide problem with health consequences, Michael F Holick, Am J Clin Nutr, April 2008, vol. 87, no. 4, 1080S-1086S.

601. The vitamin D content of fortified milk and infant formula, Holick MF, NEJM, vol. 326:1178–1181, April 30, 1992.

602. Vitamin D intoxication associated with an over-the-counter supplement, Koutikia P, N Engl J Med, July 5, 2001, 345(l):66-7.

603. Vitamin D: the underappreciated D-lightful hormone that is important for skeletal and cellular health, Holick M, Current Opinion in Endocrinology and Diabetes, February 2002, 9(l):87–98.

604. The evolution of human skin coloration, Jablonski, Nina G, and George Chaplin, Journal of Human Evolution, 39: 57-106, 2000. Исключение – североамериканские индейцы. Возможно, причина – в том, что они мигрировали далеко на север относительно недавно, или же они ели столько животных тканей, богатых витамином D, что их коже не пришлось терять меланин, чтобы позволить ультрафиолетовым лучам проникать сквозь кожу для выработки витамина в организме.

605. The protective role of melanin against UV damage in human skin, Michaela Brenner, Pho-tochem Photobiol, 2008, 84(3): 539–549.

606. Там же.

607. Ultraviolet radiation accelerates BRAF-driven melanomagenesis by targeting TP53, Viros, A, et al, Nature, 2014, 511(7510): pp. 478-82.

608. Skin aging induced by ultraviolet exposure and tobacco smoking: evidence from epidemiological and molecular studies, Lei Y, Photodermatol Photoimmunol Photomed, 2001, 17: 178–183.

609. Molecular basis of sun-induced premature skin ageing and retinoid antagonism, Fisher GJ, Nature, vol. 379(6563), January 25, 1996, pp. 335–339.

610. Eicosapentaenoic acid inhibits UV-induced MMP-1 expression in human dermal fibroblasts, Hyeon HK, Journal of Lipid Research, vol. 46, 2005, pp. 1712-20.

611. Influence of glucosamine on matrix metalloproteinase expression and activity in lipopoly-saccharide-stimulated equine chondrocytes, Byron CR, American Journal of Veterinary Research, June 2003, vol. 64, no. 6, pp. 666–671.

612. The structures of elastins and their function, Debelle L and Alix AJ, Biochimie 81, 1999, pp. 981–994.

613. The Lung: Development, Aging and the Environment, Plopper C (editor), Elsevier Publishing, 2003, p. 259.

614. Anti-oxidation and anti-wrinkling effects of jeju horse leg bone hydrolysates, Dongwook Kim, Korean J Food Sei Anim Resour, 2014, 34(6): 844–851.

615. Collagen hydrolysate intake increases skin collagen expression and suppresses matrix metalloproteinase 2 activity, Zague V, / Med Food, June 2011, 14(6):618-24, doi 10.1089/jmf.2010.0085, pub April 2011.

Глава 13

616. Gallup Poll 2012, www.gallup.com/poll/156116/Nearly-Half-Americans-Drink-Soda-Daily.aspx?utm_source=google&utm_medium=rss&utm_campaign=syndication

617. Dietary and physical activity behaviors among adults successful at weight loss maintenance, Judy Kruger, International Journal of Behavioral Nutrition and Physical Activity, December 2006, 3:17.

618. Body mass index and neurocognitive functioning across the adult lifespan, Stanek KM, Neuropsychology, March 2013, (2):141-51.

619. Altered executive function in obesity; exploration of the role of affective states on cognitive abilities, Appetite, vol. 52, issue 2, April 2009, pp. 535–539.

620. Opinion of the panel on food additives, flavourings, processing aids and food contact materials (AFC), EFSA Journal, 2008, 754, 1-34 © European Food Safety Authority, 2007 Scientific (question nos. EFSA-Q-2006-168 and EFSA-Q-2008-254, adopted on May 22, 2008.

621. Opinion of the panel on food additives, flavourings, processing aids and food contact materials (AFC), EFSA Journal 2008, 754, 1-34 © European Food Safety Authority, 2007 Scientific (question nos. EFSA-Q-2006-168 and EFSA-Q-2008-254, adopted on May 22, 2008.

622. www.webmd.com/parenting/baby/baby-food-nutrition-9/baby-food-answers

623. www.caringforkids.cps.ca/handouts/feeding_your_baby_m_the_first_year

Глава 14

624. The risk of lead contamination in bone broth diets, Medical Hypotheses, vol. 80, issue 4, April 2013, pp. 389–390.

625. Evaluation of lead content of kale (brassica oleraceae) commercially available in Buncombe County, North Carolina, Journal of the North Carolina Academy of Science, 124(1), 2008, pp. 23–25.

626. Mercury, arsenic, lead and cadmium in fish and shellfish from the Adriatic Sea, Food Addit Contam, March 2003, 20(3):241-6.

627. WebMD Report: Protein drinks have unhealthy metals, Kathleen Doheny, reviewed by Laura J. Martin on June 3, 2010. Consumer Reports study finds worrisome levels of lead, cadmium, and other metals, открыто по ссылке 8 марта 2015 года: http://www.webmd.com/food-recipes/20100603/ report-protein-drinks-have-unhealthy-metals

628. Lead in New York City community garden chicken eggs: influential factors and health implications, Environ Geochem Health, August 2014, 36(4):633-49, doi 10.1007/sl0653-013-9586-z, epub November 2013.

629. Cadmium and lead levels in milk, milk-cereal and cereal formulas for infants and children up to three years of age, Rocz Panstw Zahl Hig, 1991, 42(2):131-8.

630. Arsenic, cadmium, lead and mercury in canned sardines commercially available in eastern Kentucky, USA, Mar Pollut Bull, January 2011, 62(1).

631. Mercury, arsenic, lead and cadmium in fish and shellfish from the Adriatic Sea, Food Addit Contam, March 2003, 20(3):241-6.

632. Biochemical characterization of cyanobacterial extracellular polymers (EPS) from modern marine stromatolites (Bahamas), Alan Decho, Prep Biochem and Biotechnol, 30(4), 321–330 (2000).

633. Antioxidant and antiinflammatory activities of ventol, a phlorotannin-rich natural agent derived from Ecklonia cava, and its effect on proteoglycan degradation in cartilage explant culture, Kang K, Res Commun Mol Pathol Pharmacol, 2004, 115–116:77–95.

634. www.ionsource.com/Card/protein/beta_casein.htm

635. Comparative effects of A1 versus A2 beta-casein on gastrointestinal measures: a blinded randomised crossover pilot study, European Journal of Clinical Nutrition, 2014, 68, 994-1000.

636. Адрес инструмента CDC: at cdc.gov/foodbornoutbreaks/. Открыто по ссылке 9 марта 2016 года, период сбора данных – 1998–2014, во всех 50 штатах.

637. www.westonaprice.org/press/government-data-proves-raw-milk-safe/. Основано на данных переписи населения 2010 года.

638. Оценка основана на сообщениях, что 60 процентов взрослых в США не пьют молоко, а также на данных о детях с этого сайта: www.agriview.com/news/dairy/americans-drinking-Iess-milk-can-the-tide-be-turned/article_14ed2c88-d9bd-l Ie2-a7b9-0019bb2963f4.html

639. www.realmilk.com/press/wisconsin-campylobacter-outbreak-falsely-blamed-on-raw-milk/

640. Eating in restaurants: a risk factor for foodborne disease? Oxford Journals Medicine and Health Clinical Infectious Diseases, vol. 43, issue 10, pp. 1324–1328.

641. The ten riskiest foods regulated by the US food and drug administration, открыто по ссылке 9 марта 2016 года: www.cspinet.org/new/pdf/cspi_top_10_fda.pdf626. High intakes of milk, but not meat, increase s-insulin and insulin resistance in eight-year-old boys, C Hoppe, European Journal of Clinical Nutrition, 2005, 59, 393–398.

642. European Journal of Clinical Nutrition (2005) 59, 393–398. High intakes of milk, but not meat, increase s-insulin and insulin resistance in 8-year-old boys. C Hoppe.

643. High intake of milk, but not meat decreasses bone turnover in prepubertal boys after seven days, Eur J Clin Nutr, August 2007, 61(8):957-62, epub January 2007.

644. Animal protein intake, serum insulin-like growth factor I, and growth in healthy 2.5-year-old Danish children, Am J Clin Nutr, August 2004, 80(2):447-52. «Повышение потребления молока с 200 до 600 мл в день коррелирует с 30-процентным увеличением циркуляции IGF-I. Это говорит о том, что вещества в молоке оказывают стимулирующий эффект на концентрацию sIGF-I и, соответственно, на рост».

645. Role of the enteric microbiota in intestinal homeostasis and inflammation, Free Radic Biol Med, Mar 2014, 0: 122–133.

646. Mechanisms of disease: the role of intestinal barrier function in the pathogenesis of gastrointestinal auto-immune diseases, Alessio Fasano and Terez Shea Donohue, Nature Clinical Practice Gastroenterology and Hepatology, September 2005, vol. 2, no. 9, pp. 416–422.

647. Surprises from celiac disease, Scientific American, August 2009, pp. 32–39.

648. Gliadin, zonulin, and gut permeability: effects on celiac and non-celiac intestinal mucosa and intestinal cell lines, Alessio Fasano, Scandinavian Journal of Gastroenterology, 2006; 41: 408–419.

649. Zonulin and its regulation of intestinal barrier function: the biological door to inflammation, autoimmunity, and cancer, Physiological Reviews, January 1, 2011, vol. 91, no. 1, pp. 151–175.

650. Non-celiac gluten sensitivity: the new frontier of gluten related disorders, Nutrients,October 2013, 5(10): 3839–3853.

651. Epidemiology of food allergy, Scott H. Sicherer, March 2011, vol. 127, issue 3, pp. 594–602.

652. Toxic metal distribution in rural and urban soil samples affected by industry and traffic, Polish J of Environ Stud, vol. 18, no. 6 (2009), 1141–1150.

653. The elephant in the playground: confronting lead-contaminated soils as an important source of lead burdens to urban populations, Filippelli GM and Laidlaw MAS, 2010, Perspectives in Biology and Medicine 53, 31–45.

654. The role of immune dysfunction in the pathophysiology of autism, Brain Behav Immun, author manuscript available in PMC, March 1, 2013, Brain Behav Immun, March 2012, 26(3) pp. 383–392.

655. Is a subtype of autism an allergy of the brain? Clin Ther, May 2013, 35(5):584-91, doi 10.1016/j.clinthera.2013.04.009.

656. Focal brain inflammation and autism, / Neuroinflammation, 2013, 10: 46.

657. Sugar-sweetened carbonated beverage consumption and coronary artery calcification in asymptomatic men and women, Chun S, Choi Y, Chang Y, et al, Am Heart J, 2016; doi 10.1016/j. ahj.2016.03.018.

658. Added sugar intake and cardiovascular diseases mortality among US adults, Yang Q, Zhang Z, Gregg EW, et al, JAMA Intern Med, 2014, doi 10.1001/jamainternmed.2013.13563.

Авторы иллюстраций

«Слияние культур, слияние времени»: Flickr Creative Commons, Mark Byzewski «Что общего у самых сильных и стойких людей в истории?» Кличко: Sven Teschke; Самуэльсон: Frankie Fouganthin; Чингисхан: Fanghong; все остальные фотографии – общественное достояние

«Старомодный завтрак»: предоставлено Imam MP Heijboer «Профили генетического богатства». Жительница Таиланда: предоставлено David Miller, Flickr Creative Commons; датская официантка: ©Bill Bachman

«Восемь исторических этюдов на тему человеческой анатомии». Ле Корбюзье: Wasily Wikimedia Commons; все остальные фотографии – общественное достояние «Золотой прямоугольник», Shanahan

«Прайс встречается с Марквардтом». Фотографии © Price Pottenger Nutrition Foundation, www.PPNE.org; «маска Марквардта» © Stephen Marquardt, www. beautyanalysis.com

«Почему привлекательные люди вводят нас в транс», Shanahan «Среднее лицо», Shanahan

«Первый сын: почему ему так везет?» Мэтт Диллон: Wikimedia Commons, Festival International de Cine en Guadalajara; Кевин Диллон: Flickr Creative Commons, Allistair McMannis

«Разная геометрия». Пэрис Хилтон: Pad Schafermeier; Никки Хилтон: Eduardo Sciämmarello

«Болит шея? Be дело в двухлучевой симметрии», предоставлено Dan Shanahan «Фетальный алкогольный синдром», Modern Pharmacology, vol. 6, 1977.

«Как недоразвитая челюсть влияет на дыхательные пути», предоставлено Alexander V. Antipov, D.D.S.

«Почему мужчины должны готовиться к зачатию так же серьезно, как и женщины», предоставлено Arielle Shanahan

«Как скелет реагирует на изменение рациона», Shanahan «Изменив диету, мы изменяем себя», Shanahan «Как Кис жульничал», Shanahan

«Частичная гидрогенизация сдавливает жиры и делает их плоскими», Shanahan «Почему растительные масла склонны к окислению», Shanahan «Сердце во фритюре», Shanahan

«Как свободные радикалы повреждают мембраны», Shanahan «Липопротеины: супергерои липидной циркуляции», Shanahan «Как дисфункциональные липопротеины вызывают артериосклероз», Shanahan «Большое количество сахара в еде может привести к деменции» © 2006 National Academy of Sciences, U.S.A.

«Гидролизное разрезание», Shanahan

«Мясо внутренностей против фруктов и овощей», Shanahan Африканский петроглиф», предоставлено Andras Zboray, Fliegel Jerniczy Expeditions. Часть фотографии обработана, чтобы петроглиф лучше было видно в чернобелом цвете.

«Жиры, вызывающие воспаление, мешают избавляться от лишнего веса», Shanahan

«Правильные сигналы могут превращать жировые клетки в мышечные, костные или нервные», Shanahan

«Кормить кожу косметическим кремом…», предоставлено Reza Kafi, M.D. «Анатомия кожи», сотрудники Blausen.com, “Blausen Gallery 2014,” Wikiversity Journal of Medicine.

«Классический признак слабого коллагена», Shanahan

«У целлюлитного жира нет нормальной коллагеновой поддержки», Shanahan

«Откуда берутся шрамы», Shanahan

«Как солнце вызывает морщины», Shanahan

«Битва диет». Орниш: предоставлено Pierre Omidyar; масай: Ninara «Тест на преждевременные морщины», Shanahan

«Мозгу нравятся гладкие формы», фотографии Альфреда Ярбуса, общественное достояние

«Пропорции макроэлементов». Слева: среднестатистический рацион; справа: здоровый рацион, United States, 2015, with special feature on Racial and Ethnic Health Disparities, page 207

notes

Назад: Список рекомендованной литературы

Дальше: Примечания